Almost 25 years have passed since a mutation of a formin gene, DIAPH1, was identified as
being responsible for a human inherited disorder: a form of sensorineural hearing loss …

Leaf blight is a fungal disease that mainly affects the growth and development of leaves in
plants. To investigate the molecular mechanisms of leaf blight defense in poplar, we …

Depression is a common neuropsychiatric disease which brings an increasing burden to all
countries globally. Baicalin, a flavonoid extracted from the dried roots of Scutellaria, has …

Background Surgical resection followed by indicated adjuvant therapy offers potential
curative treatment in colonic adenocarcinoma. Beyond the well-established seed and soil …

Abstract Cytoskeleton-associated protein 2-like (CKAP2L) is a mitotic spindle protein and its
high expression is reported to be associated with the poor prognosis of cancer patients …

Background Cellular senescence plays an irreplaceable role in tumorigenesis, progression,
and tumor microenvironment (TME) remodeling. However, to date, there is limited research …

Objective Bladder cancer is a clinical and social conundrum due to its high incidence and
recurrence rate. It is urgent to find new targets for the diagnosis and treatment of bladder …

Background Colorectal cancer (CRC) is a common global malignancy associated with high
invasiveness, high metastasis, and poor prognosis. CRC commonly metastasizes to the …

The lignified tissue in the secondary stem is the main source of wood. In this study, we
applied RNA-Seq analysis to the poplar stems in three developmental stages, including …

Background: Cyclin F (CCNF) represents a pivotal constituent within the family of cell cycle
proteins, which also belongs to the F-box protein family and acts as a critical regulatory …