Pancreatic cancer is a leading cause of cancer death worldwide and its global burden has
more than doubled over the past 25 years. The highest incidence regions for pancreatic …

Genetic risk variants that have been identified in genome-wide association studies of
complex diseases are primarily non-coding. Translating these risk variants into mechanistic …

Inherited genetic factors play an important role in the development of pancreatic cancer, with
approximately 2136% of pancreatic cancer being due to genetic variation. Approximately 5 …

There are several types of pancreatic cancer, but the most common type is pancreatic
adenocarcinoma, which comprises 90% of all pancreatic cancer diagnoses. This review …

Genes carrying high‐penetrance germline mutations may also be associated with cancer
susceptibility through common low‐penetrance genetic variants. To increase the knowledge …

Pancreatic cancer (PC), particularly its most common form, pancreatic ductal
adenocarcinoma (PDAC), is relatively rare but highly lethal. Knowledge about PC risk …

Pancreatic cancer is a highly aggressive malignancy that features high recurrence rates and
the poorest prognosis of all solid cancers. The urokinase plasminogen activation system …

Introduction Only a small number of risk factors for pancreatic ductal adenocarcinoma
(PDAC) has been established. Several studies identified a role of epigenetics and of …

Pancreatic ductal adenocarcinoma (PDAC) has high mortality and rising incidence rates.
Recent data indicate that the gut microbiome and associated metabolites may play a role in …

Non-coding RNAs have an integral regulatory role in numerous functions related to lung
cancer development. Here, we report identification of a novel lncRNA, termed T P53-i …