Glycosylation is how proteins and lipids are modified with complex carbohydrates known as
glycans. The post-translational modification of proteins with glycans is not a template-driven …

The increasing demand for biosimilar monoclonal antibodies (mAbs) has prompted the
development of stable high-producing cell lines while simultaneously decreasing the time …

N‐linked glycosylation is one of the most important post‐translational modifications of
monoclonal antibodies (mAbs) and is considered to be a critical quality attribute (CQA), as …

For industrial production of recombinant protein biopharmaceuticals, Chinese hamster ovary
(CHO) cells represent the most widely adopted host cell system, owing to their capacity to …

There are numerous applications for recombinant antibodies (rAbs) in biological and
toxicological research. Monoclonal antibodies are synthesized using genetic engineering …

摘要基因功能的解析是现代生物学研究的基本问题, 基因的精准, 高效和靶向编辑是基因功能
研究不可或缺的手段. 在过去的30 多年, 基因编辑实现了从基于同源重组修复技术的基因打靶 …

The N-linked glycosylation profile of (monoclonal) antibodies (mAb) is a critical product
quality attribute due to its effect on antibody-dependent cellular cytotoxicity. As a …