The smart targeting of nanoparticles

AD Friedman, SE Claypool… - Current pharmaceutical …, 2013 - ingentaconnect.com
One major challenge in nanomedicine is the selective delivery of nanoparticles to diseased
tissues. Nanoparticle delivery systems require targeting for specific delivery to pathogenic …

[HTML][HTML] Off to the organelles-killing cancer cells with targeted gold nanoparticles

M Kodiha, YM Wang, E Hutter, D Maysinger… - Theranostics, 2015 - ncbi.nlm.nih.gov
Gold nanoparticles (AuNPs) are excellent tools for cancer cell imaging and basic research.
However, they have yet to reach their full potential in the clinic. At present, we are only …

Surface functionalization of gold nanoparticles for targeting the tumor microenvironment to improve antitumor efficiency

KF Tan, LLA In, P Vijayaraj Kumar - ACS applied bio materials, 2023 - ACS Publications
Gold nanoparticles (AuNPs) have undergone significant research for their use in the
treatment of cancer. Numerous researchers have established their potent antitumor …

Gold and silver nanoparticles for applications in theranostics

P Di Pietro, G Strano, L Zuccarello… - Current topics in …, 2016 - ingentaconnect.com
Noble metal nanomaterials, such as gold or silver nanoparticles, exhibit unique photonic,
electronic, catalytic and therapeutic properties. The high versatility in their synthesis …

Advances in the design of amino acid and peptide synthesized gold nanoparticles for their applications

A Rai, S Seena, T Gagliardi, PJ Palma - Advances in Colloid and Interface …, 2023 - Elsevier
The field of therapeutics and diagnostics is advanced by nanotechnology-based
approaches including the spatial-temporal release of drugs, targeted delivery, enhanced …

[HTML][HTML] Enhanced intracellular translocation and biodistribution of gold nanoparticles functionalized with a cell-penetrating peptide (VG-21) from vesicular stomatitis …

PM Tiwari, E Eroglu, SS Bawage, K Vig, ME Miller… - Biomaterials, 2014 - Elsevier
Reduced toxicity and ease of modification make gold nanoparticles (GNPs) suitable for
targeted delivery, bioimaging and theranostics by conjugating cell-penetrating peptides …

Biologically inspired stealth peptide-capped gold nanoparticles

AK Nowinski, AD White, AJ Keefe, S Jiang - Langmuir, 2014 - ACS Publications
Introduction into the human body makes most nanoparticle systems susceptible to
aggregation via nonspecific protein binding. Here, we developed a peptide-capped gold …

Antibiotic gold: tethering of antimicrobial peptides to gold nanoparticles maintains conformational flexibility of peptides and improves trypsin susceptibility

P Wadhwani, N Heidenreich, B Podeyn, J Bürck… - Biomaterials …, 2017 - pubs.rsc.org
Peptide-coated nanoparticles are valuable tools for diverse biological applications, such as
drug delivery, molecular recognition, and antimicrobial action. The functionalization of pre …

Peptide-metal nanohybrids (PMN): Promising entities for combating neurological maladies

A Kour, HS Panda, IR Singh, A Kumar… - Advances in Colloid and …, 2023 - Elsevier
Nanotherapeutics are gaining traction in the modern scenario because of their unique and
distinct properties which separate them from macro materials. Among the nanoparticles …

Dynamics and self-assembly of bio-functionalized gold nanoparticles in solution: Reactive molecular dynamics simulations

S Monti, G Barcaro, L Sementa, V Carravetta, H Ågren - Nano Research, 2018 - Springer
The self-assembling properties, stability, and dynamics of hybrid nanocarriers (gold
nanoparticles (AuNPs) functionalized with cysteine-based peptides) in solution are studied …