Transparent neural implantable devices: a comprehensive review of challenges and progress
The key to designing an implantable device lies in condensing the synergistic effects of
diagnostic and therapeutic methods in a single tool. In conjunction with the integration of …
diagnostic and therapeutic methods in a single tool. In conjunction with the integration of …
Early brain activity: translations between bedside and laboratory
Neural activity is both a driver of brain development and a readout of developmental
processes. Changes in neuronal activity are therefore both the cause and consequence of …
processes. Changes in neuronal activity are therefore both the cause and consequence of …
FTO-dependent m6A modification of Plpp3 in circSCMH1-regulated vascular repair and functional recovery following stroke
B Li, W Xi, Y Bai, X Liu, Y Zhang, L Li, L Bian… - Nature …, 2023 - nature.com
Vascular repair is considered a key restorative measure to improve long-term outcomes after
ischemic stroke. N 6-methyladenosine (m6A), the most prevalent internal modification in …
ischemic stroke. N 6-methyladenosine (m6A), the most prevalent internal modification in …
Platelet Membrane Biomimetic Magnetic Nanocarriers for Targeted Delivery and in Situ Generation of Nitric Oxide in Early Ischemic Stroke
Early diagnosis and treatment of acute ischemic stroke poses a significant challenge due to
its suddenness and short therapeutic time window. Human endogenous cells derived …
its suddenness and short therapeutic time window. Human endogenous cells derived …
[HTML][HTML] Platelet bio-nanobubbles as microvascular recanalization nanoformulation for acute ischemic stroke lesion theranostics
Since the expected therapeutic results of ischemic stroke are strictly time dependent, early
and accurate diagnosis as well as short intervals between diagnosis and treatment are key …
and accurate diagnosis as well as short intervals between diagnosis and treatment are key …
[HTML][HTML] Gaining insight into the neural basis of resting-state fMRI signal
The blood oxygenation level-dependent (BOLD)-based resting-state functional magnetic
resonance imaging (rsfMRI) has been widely used as a non-invasive tool to map brain-wide …
resonance imaging (rsfMRI) has been widely used as a non-invasive tool to map brain-wide …
Synchronized astrocytic Ca2+ responses in neurovascular coupling during somatosensory stimulation and for the resting state
The role of astrocytes in neurovascular coupling (NVC) is unclear. Here, we applied a
multimodality imaging approach to concomitantly measure synchronized neuronal or …
multimodality imaging approach to concomitantly measure synchronized neuronal or …
Iptakalim improves cerebral microcirculation in mice after ischemic stroke by inhibiting pericyte contraction
R Guo, Y Dong, Z Yin, Z Cai, J Yang, J Ji… - Acta Pharmacologica …, 2022 - nature.com
Pericytes are present tight around the intervals of capillaries, play an essential role in
stabilizing the blood–brain barrier, regulating blood flow and immunomodulation, and …
stabilizing the blood–brain barrier, regulating blood flow and immunomodulation, and …
Development of a Monte Carlo-wave model to simulate time domain diffuse correlation spectroscopy measurements from first principles
Significance: Diffuse correlation spectroscopy (DCS) is an optical technique that measures
blood flow non-invasively and continuously. The time-domain (TD) variant of DCS, namely …
blood flow non-invasively and continuously. The time-domain (TD) variant of DCS, namely …
Intrinsic, widefield optical imaging of hemodynamics in rodent models of Alzheimer's disease and neurological injury
The complex cerebrovascular network is critical to controlling local cerebral blood flow
(CBF) and maintaining brain homeostasis. Alzheimer's disease (AD) and neurological injury …
(CBF) and maintaining brain homeostasis. Alzheimer's disease (AD) and neurological injury …