The melanocortin pathway and control of appetite-progress and therapeutic implications

G Baldini, KD Phelan - Journal of Endocrinology, 2019 - joe.bioscientifica.com
The initial discovery that ob/ob mice become obese because of a recessive mutation of the
leptin gene has been crucial to discover the melanocortin pathway to control appetite. In the …

Melanocortins and Their Potential for the Treatment, Prevention and Amelioration of Complications of Diabetes

GN Robinson, RJ Pickering - Diabetology, 2024 - mdpi.com
Diabetes mellitus (type I and II) is an advancing global health problem, concerningly
increasing in prevalence in most of the developed and developing world. Current therapies …

[图书][B] Contextual Induction of Non-Shivering Thermogenesis and Skeletal Muscle Futile Calcium Cycling in Two Rat Models

LA Heemstra - 2021 - search.proquest.com
More than a third of the world's adults are overweight or obese; people with obesity have
increased risk of mortality and multiple diseases. We discovered a novel phenomenon with …