Bladder cancer is a global health issue with sex differences in incidence and prognosis.
Bladder cancer has distinct molecular subtypes with multiple pathogenic pathways …

The field of research in bladder cancer has seen significant advances in recent years. Next-
generation sequencing has identified the genes most mutated in bladder cancer. This …

Simple Summary As our knowledge of cancer as a complex organ comprising tumor cells as
well as surrounding cells within the microenvironment continues to grow, it is imperative to …

Cancer associated fibroblasts (CAF) and the extracellular matrix (ECM) produced by them
have been recognized as key players in cancer biology and emerged as important targets …

Abstract Background Cancer-associated fibroblasts (CAFs) are molecularly heterogeneous
mesenchymal cells that interact with malignant cells and immune cells and confer anti-and …

Bladder cancer is a prevalent but currently understudied cancer type and patient outcomes
are poor when it progresses to the muscle-invasive stage. Current research in bladder …

Over the past decade, T cell immunotherapy has changed the face of cancer treatment,
providing robust treatment options for several previously intractable cancers. Unfortunately …

Abstract Aim/Purpose Fibroblast activation protein-(FAP)-ligands, a novel class of tracers for
PET/CT imaging, demonstrated promising results in previous studies in various …

Background Cancer immunity is based on the interaction of a multitude of cells in the spatial
context of the tumour tissue. Clinically relevant immune signatures are therefore anticipated …

Simple Summary Urothelial bladder carcinoma entails significant health costs due to the
high recurrence rates and poor response to standard cisplatin-based treatment. The …