Cyclooxygenase (COX), the key enzyme required for the conversion of arachidonic acid to
prostaglandins was first identified over 20 years ago. Drugs, like aspirin, that inhibit …

Paracetamol (acetaminophen) is undoubtedly one of the most widely used drugs worldwide.
As an over-the-counter medication, paracetamol is the standard and first-line treatment for …

▪ Abstract Cyclooxygenase (COX), also known as prostaglandin endoperoxide synthase, is
the key enzyme required for the conversion of arachidonic acid to prostaglandins. Two COX …

The effect of novel pyrazolines, 3-methyl-5-hydroxy-5-trichloromethyl-4, 5-dihydro-1H-
pyrazole-1-carboxyamide (MPCA) and 3-phenyl-5-hydroxy-5-trichloromethyl-4, 5-dihydro …

Background: Nonsteroidal anti-inflammatory drugs (NSAID) may be useful in the treatment of
AD. Clinical and laboratory experience with nimesulide, an NSAID with preferential …

Originally suggested to function mainly in inflammatory situations, recent data have implied
important roles for the cyclooxygenase-2 isoenzyme in reproductive biologic processes …

Epidemiological studies show that some nonsteroidal anti-inflammatory drugs, nonspecific
inhibitors of the cyclooxygenase enzyme, reduce the incidence of Alzheimer's disease (AD) …

This study demonstrates the removal efficiency and the permeate flux behavior during cross-
flow nanofiltration (NF) of aqueous solutions of five pharmaceutically active compounds …

Nimesulide, a non‐steroidal anti‐inflammatory drug (NSAID), is administered orally or
rectally twice daily for a variety of inflammation and pain states. This is a unique NSAID, not …

Following the discovery of inducible COX-2 in arthritic joint fluid and immunocompetent cells
a revolution in the field of antiinflammatory treatment was expected. The detection of a …