As part of the neurovascular unit, the blood-brain barrier (BBB) is a unique, dynamic
regulatory boundary that limits and regulates the exchange of molecules, ions, and cells …

The endothelial cells lining the brain capillaries separate the blood from the brain
parenchyma. The endothelial monolayer of the brain capillaries serves both as a crucial …

Advancements in molecular biology have led to a greater understanding of the individual
proteins responsible for generating cerebral edema. In large part, the study of cerebral …

Central nervous system (CNS) barriers predominantly mediate the immune-privileged status
of the brain, and are also important regulators of neuroimmune communication. It is …

The blood-brain barrier (BBB) is comprised of brain microvascular endothelial central
nervous system (CNS) cells, which communicate with other CNS cells (astrocytes, pericytes) …

Structural alterations and breakdown of the blood brain barrier (BBB) is often a primary or
secondary consequence of disease, resulting in brain oedema and the transport of …

Breakdown of the inner endothelial blood-retinal barrier (BRB), as occurs in diabetic
retinopathy, age-related macular degeneration, retinal vein occlusions, uveitis and other …

Pericytes play a key role in the development of cerebral microcirculation. The exact role of
pericytes in the neurovascular unit in the adult brain and during brain aging remains …

The blood–brain barrier (BBB) is a term used to describe a series of properties possessed
by the vasculature of the central nervous system (CNS) that tightly regulate the movement of …

Blood-brain barrier (BBB) models are often used to investigate BBB function and screen
brain-penetrating therapeutics, but it has been difficult to construct a human model that …