Reviewing Colchicaceae alkaloids–perspectives of evolution on medicinal chemistry

S Larsson, N Ronsted - Current topics in medicinal chemistry, 2014 - ingentaconnect.com
The subject of chemosystematics has provided insight to both botanical classification and
drug development. However, degrees of subjectivity in botanical classifications and limited …

Importance of Colchicum species in modern therapy and its significance in Turkey

GG Toplan, Ç Gürer, A Mat - Journal of Faculty of Pharmacy of …, 2016 - dergipark.org.tr
Colchicum species, which are widely used as medication for many years, still remain
important in treatment. Some of them are cultivated to be used for pharmaceutical industry …

Chemical and molecular characterization of metabolites from Flavobacterium sp.

V Enisoglu-Atalay, B Atasever-Arslan, B Yaman… - PloS one, 2018 - journals.plos.org
In this study, a Flavobacterium sp. is isolated from natural spring, and identified using
molecular techniques. Extracellular and intracellular secondary metabolites are identified …

Phospholipidic colchicinoids as promising prodrugs incorporated into enzyme-responsive liposomes: chemical, biophysical, and enzymological aspects

ES Shchegravina, DS Tretiakova… - Bioconjugate …, 2019 - ACS Publications
Enzyme-responsive liposomes release their cargo in response to pathologically increased
levels of enzymes at the target site. We report herein an assembly of phospholipase A2 …

[HTML][HTML] Phytochemical profiles, physicochemical analysis, and biological activity of three Colchicum species

A Davoodi, M Azadbakht, SJ Hosseinimehr… - Jundishapur Journal of …, 2021 - brieflands.com
Background: Colchicum is a genus of the Colchicaceae family with various isolated
compounds, especially tropolone alkaloids and flavonoids, which are used for osteoarthritis …

Screening of new antileukemic agents from essential oils of algae extracts and computational modeling of their interactions with intracellular signaling nodes

B Atasever-Arslan, K Yilancioglu, Z Kalkan… - European Journal of …, 2016 - Elsevier
Microalgae are very rich in bioactive compounds, minerals, polysaccharides, poly-
unsaturated fatty acids and vitamins, and these rich constituents make microalgae an …

Tropolone alkaloids from Colchicum kurdicum (Bornm.) Stef.(Colchicaceae) as the potent novel antileishmanial compounds; purification, structure elucidation …

M Azadbakht, A Davoodi, SJ Hosseinimehr… - Experimental …, 2020 - Elsevier
Natural compounds played an important role for prevention and treatment of the disease as
well as are the important compounds for the design of the new bioactive compounds. In this …

[HTML][HTML] Apoptotic effect of Nigella sativa on human lymphoma U937 cells

BA Arslan, FB Isik, H Gur, F Ozen… - Pharmacognosy …, 2017 - ncbi.nlm.nih.gov
Objective: Nigella sativa is from botanical Ranunculaceae family and commonly known as
black seed. Apoptotic effect of N. sativa and its apoptotic signaling pathways on U937 …

[PDF][PDF] Cytotoxic effect of extract from Dunaliella salina against SH-SY5Y neuroblastoma cells

B Atasever-Arslan, K Yilancioglu, MG Bekaroglu… - Gen Physiol …, 2015 - academia.edu
Cytotoxic effects of essential oils extracted from Dunaliella salina on SH-SY5Y human
neuroblastoma cells were investigated in this study. GC-MS analysis was used for …

Chemical Constituents of the Different Parts of Colchicum micranthum and C. chalcedonicum and their Cytotoxic Activities

G Gulsoy-Toplan, F Goger… - Natural Product …, 2018 - journals.sagepub.com
Colchicum species, which have been widely used as a medication for years, still remain
important in treatment of Familial Mediterranean Fever, gout and Behcet's Disease. In the …