[HTML][HTML] Emergent CRISPR–Cas-based technologies for engineering non-model bacteria
Highlights•CRISPR–Cas systems promoted the engineering of non-model bacteria.•Tools
include genome modifications and finely-tuned transcriptional regulation.•CRISPR–Cas …
include genome modifications and finely-tuned transcriptional regulation.•CRISPR–Cas …
Stepping on the gas to a circular economy: accelerating development of carbon-negative chemical production from gas fermentation
N Fackler, BD Heijstra, BJ Rasor… - Annual review of …, 2021 - annualreviews.org
Owing to rising levels of greenhouse gases in our atmosphere and oceans, climate change
poses significant environmental, economic, and social challenges globally. Technologies …
poses significant environmental, economic, and social challenges globally. Technologies …
Pollution to products: recycling of 'above ground'carbon by gas fermentation
M Köpke, SD Simpson - Current Opinion in Biotechnology, 2020 - Elsevier
Climate crisis and rapid population growth are posing some of the most urgent challenges to
mankind and have intensified the need for the deployment of carbon recycling and carbon …
mankind and have intensified the need for the deployment of carbon recycling and carbon …
Genetic manipulation of the human gut bacterium Eggerthella lenta reveals a widespread family of transcriptional regulators
Eggerthella lenta is a prevalent human gut Actinobacterium implicated in drug, dietary
phytochemical, and bile acid metabolism and associated with multiple human diseases. No …
phytochemical, and bile acid metabolism and associated with multiple human diseases. No …
Advances in systems metabolic engineering of autotrophic carbon oxide-fixing biocatalysts towards a circular economy
High levels of anthropogenic CO 2 emissions are driving the warming of global climate. If
this pattern of increasing emissions does not change, it will cause further climate change …
this pattern of increasing emissions does not change, it will cause further climate change …
Genome-wide CRISPRi screen identifies enhanced autolithotrophic phenotypes in acetogenic bacterium Eubacterium limosum
Acetogenic bacteria are a unique biocatalyst that highly promises to develop the sustainable
bioconversion of carbon oxides (eg, CO and CO2) into multicarbon biochemicals. Genotype …
bioconversion of carbon oxides (eg, CO and CO2) into multicarbon biochemicals. Genotype …
Production of the biocommodities butanol and acetone from methanol with fluorescent FAST-tagged proteins using metabolically engineered strains of Eubacterium …
M Flaiz, G Ludwig, FR Bengelsdorf, P Dürre - Biotechnology for Biofuels, 2021 - Springer
Background The interest in using methanol as a substrate to cultivate acetogens increased
in recent years since it can be sustainably produced from syngas and has the additional …
in recent years since it can be sustainably produced from syngas and has the additional …
Genetic and metabolic engineering challenges of C1-gas fermenting acetogenic chassis organisms
Unabated mining and utilisation of petroleum and petroleum resources and their conversion
to essential fuels and chemicals have drastic environmental consequences, contributing to …
to essential fuels and chemicals have drastic environmental consequences, contributing to …
Synthetic or natural? Metabolic engineering for assimilation and valorization of methanol
PA Sanford, BM Woolston - Current Opinion in Biotechnology, 2022 - Elsevier
Highlights•Synthetic methylotrophy achieved in E. coli via ribulose monophosphate
cycle.•Synthetic methylotrophy has been achieved in E. coli via reductive glycine …
cycle.•Synthetic methylotrophy has been achieved in E. coli via reductive glycine …
Synthetic biology on acetogenic bacteria for highly efficient conversion of C1 gases to biochemicals
Synthesis gas, which is mainly produced from fossil fuels or biomass gasification, consists of
C1 gases such as carbon monoxide, carbon dioxide, and methane as well as hydrogen …
C1 gases such as carbon monoxide, carbon dioxide, and methane as well as hydrogen …