The aging process is driven by multiple mechanisms that lead to changes in energy
production, oxidative stress, homeostatic dysregulation and eventually to loss of functionality …

Malaria, particularly Plasmodium falciparum, continues to disproportionately affect pregnant
women. In addition to the profoundly deleterious impact of maternal malaria on the health of …

Malaria causes tremendous early childhood morbidity and mortality, providing an urgent
impetus for the development of a vaccine that is effective in neonates. However, the infant …

Background Intermittent preventive treatment of malaria in pregnancy (IPTp) with
dihydroartemisinin-piperaquine (IPTp-DP) has been shown to reduce the burden of malaria …

Background Intermittent preventive treatment of malaria during pregnancy (IPTp) with
dihydroartemisinin-piperaquine (DP) significantly reduces the burden of malaria during …

The BCG vaccine protects non-specifically against other diseases than tuberculosis. Three
randomised controlled trials of early BCG in Guinea-Bissau found a 38% reduction in all …

Despite the high burden of malaria worldwide, there is surprisingly scarce research on sex-
based differences in malaria outside of pregnancy. A more thorough understanding of …

Boys present with higher proportions of immature/naïve CD5+ B cells than girls up to 3 years
of age. Boys also have higher fractions of regulatory T cells (Tregs) in early infancy, but the …

Background Placental malaria (PM) has been associated with a higher risk of malaria during
infancy. However, it is unclear whether this association is causal, and is modified by infant …

Background Maternal obesity (MO) is associated with a higher risk of immune‐mediated
diseases in the offspring and higher leptin levels in cord blood (CB). This study evaluates …