Sorafenib is a multikinase inhibitor capable of facilitating apoptosis, mitigating angiogenesis
and suppressing tumor cell proliferation. In late-stage hepatocellular carcinoma (HCC) …

Gastric cancer is a deadly disease and remains the third leading cause of cancer-related
death worldwide. The 5-year overall survival rate of patients with early-stage localized …

Background Sorafenib resistance is a key impediment to successful treatment of patients
with advanced hepatocellular carcinoma (HCC) and recent studies have reported reversal of …

Sorafenib is the first-line treatment for advanced hepatocellular carcinoma (HCC). However,
it is difficult to alleviate this disease process using single-agent chemotherapy. Using …

Primary liver cancer is the sixth most common cancer and the third most common cause of
cancer-related deaths worldwide. Hepatocellular carcinoma (HCC) is a major histologic type …

Simple Summary Autophagy is a self-eating mechanism that is involved in the degradation
of organelles and cellular materials. It is initiated by intracellular and extracellular stress …

Hepatocellular carcinoma (HCC) metabolism is redirected to glycolysis to enhance the
production of metabolic compounds employed by cancer cells to produce proteins, lipids …

Li Y, Chen G, Han Z, Cheng H, Qiao L, Li Y. Onco Targets Ther. 2020; 13: 9721–9730. The
Editor and Publisher of OncoTargets and Therapy wish to retract the published article …

Despite pharmacological advances such as lenvatinib approval, therapeutic failure of
hepatocellular carcinoma (HCC) remains a big challenge due to the complexity of its …

Melatonin (N-acetyl-5-methoxytryptamine) is an indoleamine with antioxidant, chronobiotic
and anti-inflammatory properties; reduced levels of this hormone are associated with higher …