The MultiBac baculovirus/insect cell expression vector system for producing complex protein biologics

D Sari, K Gupta, DBTG Raj, A Aubert, P Drncová… - … Technologies for Protein …, 2016 - Springer
Multiprotein complexes regulate most if not all cellular functions. Elucidating the structure
and function of these complex cellular machines is essential for understanding biology …

Influenza virus neuraminidase (NA): a target for antivirals and vaccines

A Jagadesh, AAA Salam, PP Mudgal, G Arunkumar - Archives of virology, 2016 - Springer
Influenza, the most common infectious disease, poses a great threat to human health
because of its highly contagious nature and fast transmissibility, often leading to high …

Biosynthesis of a VLP-type nanocarrier specific to cancer cells using the BEVS expression system for targeted drug delivery

MS Hashemzadeh, N Gharari - Journal of Genetic Engineering and …, 2023 - Springer
Objective Canine parvovirus (CPV) is a small virus without an envelope that consists of three
viral proteins including VP1, VP2, and VP3. Exclusively, the VP2 can form a typically CPV …

Characterization of humoral responses induced by an H7N9 influenza virus-like particle vaccine in BALB/c mice

L Zhang, J Lu, Y Chen, F Shi, H Yu, C Huang, L Cui… - Viruses, 2015 - mdpi.com
In April 2013, human infections with a novel avian influenza (H7N9) virus emerged in China.
It has caused serious concerns for public health throughout the world. However, there is …

[PDF][PDF] The reoccurrence of H5N1 outbreaks necessitates the development of safe and effective influenza vaccine technologies for the prevention and control of avian …

B Yakubu, AJ Nok, OA Owolodun, PD Luka… - Biotech. Mol. Biol …, 2015 - researchgate.net
Africa is experiencing reoccurrence of avian influenza outbreaks with huge negative impact
on the economy of the continent as a result of high mortality rate and extreme …

Bacillus subtilis as a host for recombinant hemagglutinin production of the influenza a (H5N1) virus

M Aliakbari, F Behzadian, AA Deldar - Iranian Journal of Virology, 2015 - journal.isv.org.ir
Abstract Background and Aims: Influenza A (H5N1) viruses circulating in animals might
evolve and acquire the ability to spread from human to human and thus start a pandemic …

Secretory expression of hemagglutinin globular domain (HA1) of the influenza A (H5N1) virus in Bacillus subtilis

M Aliakbari, F Behzadian, AA Deldar, B Mahyad… - Iranian Journal of …, 2015 - ijmm.ir
Materials and Methods: HA1 sequence was cloned into pGEM® 5Zf (–) vector. It was then
subcloned into shuttle vector PHT43 and transferred to E. coli for replication. The …

Prokaryotic Expression of the Influenza A (H5N1) Neuraminidase

Z Latif, B Farahmand, M Saleh… - Journal of Mazandaran …, 2021 - jmums.mazums.ac.ir
Background and purpose: Highly Pathogenic Influenza A (H5N1) viruses cause vast
economic losses throughout the world. They may circulate in animals and be able to spread …

[HTML][HTML] Construction of recombinant fusion protein of influenza, a virus neuraminidase and heat shock protein 70 gene: expression in baculovirus and bioactivity

MM Pour, H Keivani, SH Masoudi… - Journal of Medicine …, 2015 - ncbi.nlm.nih.gov
Background: Two structural antigens, hemagglutinin and neuraminidase, are a major
component for the development of influenza vaccine candidates. Recombinant vaccines are …

[PDF][PDF] Baculovirus surface display of influenza virus haemagglutinin and its potential as a vaccine

RA ABDULSAHIB - 2018 - core.ac.uk
Based on data obtained from the World Health Organization (WHO), influenza (or flu) is
responsible for highly contagious, acute respiratory diseases in humans. These diseases …