Human cytomegalovirus (HCMV) is a herpesvirus that infects~ 60% of adults in developed
countries and more than 90% in developing countries. Usually, it is controlled by a vigorous …

The coordinated activities of innate and adaptive immunity are critical for effective protection
against viruses. To counter this, some viruses have evolved sophisticated strategies to …

The outcome of infection is dependent on the ability of viruses to manipulate the infected cell
to evade immunity, and the ability of the immune response to overcome this evasion …

Proteomics experiments commonly aim to estimate and detect differential abundance across
all expressed proteins. Within this experimental design, some of the most challenging …

Human cytomegalovirus (HCMV) extensively modulates host cells, downregulating> 900
human proteins during viral replication and degrading≥ 133 proteins shortly after infection …

Human cytomegalovirus (HCMV) is an important pathogen with multiple immune evasion
strategies, including virally facilitated degradation of host antiviral restriction factors. Here …

Human cytomegalovirus (HCMV) is a ubiquitous double-stranded DNA virus belonging to
the β-subgroup of the herpesvirus family. After the initial infection, the virus establishes …

Natural killer (NK) cells are cytotoxic effector cells that target and lyse virally infected cells;
many viruses therefore encode mechanisms to escape such NK cell killing. Here, we …

Human cytomegalovirus (HCMV) is the most common vertically transmitted infection
worldwide, yet there are no vaccines or therapeutics to prevent congenital HCMV (cCMV) …

The recent approval of letermovir marks a new era of therapy for human cytomegalovirus
(HCMV) infections, particularly for the prevention of HCMV disease in hematopoietic stem …