Plasmodium helical interspersed subtelomeric (PHIST) proteins, at the center of host cell remodeling

JD Warncke, I Vakonakis, HP Beck - Microbiology and Molecular …, 2016 - Am Soc Microbiol
During the asexual cycle, Plasmodium falciparum extensively remodels the human
erythrocyte to make it a suitable host cell. A large number of exported proteins facilitate this …

The human malaria parasite Plasmodium falciparum can sense environmental changes and respond by antigenic switching

VM Schneider, JE Visone, CT Harris… - Proceedings of the …, 2023 - National Acad Sciences
The primary antigenic and virulence determinant of the human malaria parasite Plasmodium
falciparum is a variant surface protein called PfEMP1. Different forms of PfEMP1 are …

Genomes of cryptic chimpanzee Plasmodium species reveal key evolutionary events leading to human malaria

SA Sundararaman, LJ Plenderleith, W Liu… - Nature …, 2016 - nature.com
African apes harbour at least six Plasmodium species of the subgenus Laverania, one of
which gave rise to human Plasmodium falciparum. Here we use a selective amplification …

Chondroitin sulfate-degrading enzymes as tools for the development of new pharmaceuticals

R Benito-Arenas, SG Zárate, J Revuelta, A Bastida - Catalysts, 2019 - mdpi.com
Chondroitin sulfates are linear anionic sulfated polysaccharides found in biological tissues,
mainly within the extracellular matrix, which are degraded and altered by specific lyases …

Expansion of lysine-rich repeats in Plasmodium proteins generates novel localization sequences that target the periphery of the host erythrocyte

HM Davies, K Thalassinos, AR Osborne - Journal of Biological Chemistry, 2016 - ASBMB
Repetitive low complexity sequences, mostly assumed to have no function, are common in
proteins that are exported by the malaria parasite into its host erythrocyte. We identify a …

Plasmodium falciparum Acetyl-CoA Synthetase Is Essential for Parasite Intraerythrocytic Development and Chromatin Modification

IO Prata, EFG Cubillos, A Kruger… - ACS Infectious …, 2021 - ACS Publications
The malaria parasite Plasmodium falciparum possesses a unique Acetyl-CoA Synthetase
(PfACS), which provides acetyl moieties for different metabolic and regulatory cellular …

Regulation of PfEMP1–VAR2CSA translation by a Plasmodium translation-enhancing factor

S Chan, A Frasch, CS Mandava, JH Ch'Ng… - Nature …, 2017 - nature.com
Pregnancy-associated malaria commonly involves the binding of Plasmodium falciparum-
infected erythrocytes to placental chondroitin sulfate A (CSA) through the PfEMP1 …

Genome-Wide Analysis of the Malaria Parasite Plasmodium falciparum Isolates From Togo Reveals Selective Signals in Immune Selection-Related Antigen Genes

K Kassegne, K Komi Koukoura, HM Shen… - Frontiers in …, 2020 - frontiersin.org
Malaria is a public health concern worldwide, and Togo has proven to be no exception.
Effective approaches to provide information on biological insights for disease elimination are …

Stringent Selection of Knobby Plasmodium falciparum-Infected Erythrocytes during Cytoadhesion at Febrile Temperature

M Dörpinghaus, F Fürstenwerth, LK Roth, P Bouws… - Microorganisms, 2020 - mdpi.com
Changes in the erythrocyte membrane induced by Plasmodium falciparum invasion allow
cytoadhesion of infected erythrocytes (IEs) to the host endothelium, which can lead to severe …

First comprehensive proteome analysis of lysine crotonylation in Streptococcus agalactiae, a pathogen causing meningoencephalitis in teleosts

X Chen, B Fan, C Fan, Z Wang, E Wangkahart… - Proteome Science, 2021 - Springer
Backgroud Streptococcus agalactiae is a common colonizer of the rectovaginal tract and
lead to infectious diseases of neonatal and non-pregnant adults, which also causes …