The CALIPR framework for highly accelerated myelin water imaging with improved precision and sensitivity

AV Dvorak, D Kumar, J Zhang, G Gilbert, S Balaji… - Science …, 2023 - science.org
Quantitative magnetic resonance imaging (MRI) techniques are powerful tools for the study
of human tissue, but, in practice, their utility has been limited by lengthy acquisition times …

[HTML][HTML] Testing the Structural Disconnection Hypothesis: Myelin Content Correlates with Memory in Healthy Aging

AM Colmenares, ML Thomas, C Anderson… - Neurobiology of …, 2024 - Elsevier
ABSTRACT INTRODUCTION The" structural disconnection" hypothesis of cognitive aging
suggests that deterioration of white matter (WM), especially myelin, results in cognitive …

Imaging of the superficial white matter in health and disease

PC Van Dyken, AR Khan, L Palaniyappan - Imaging Neuroscience, 2024 - direct.mit.edu
The superficial white matter, the layer of white matter immediately deep to the cortical grey
matter, is a highly complex, heterogeneous tissue region comprising dense meshes of …

Characterization of the orientation dependence of magnetization transfer measures in single and crossing‐fiber white matter

P Karan, M Edde, G Gilbert, M Barakovic… - Magnetic …, 2024 - Wiley Online Library
Purpose To fully characterize the orientation dependence of magnetization transfer (MT) and
inhomogeneous MT (ihMT) measures in the whole white matter (WM), for both single‐fiber …

T1 relaxation and axon fibre configuration in human white matter

G Hutchinson, J Thotland, PK Pisharady… - NMR in …, 2024 - Wiley Online Library
Understanding the effects of white matter (WM) axon fibre microstructure on T1 relaxation is
important for neuroimaging. Here, we have studied the interrelationship between T1 and …

Widespread drastic reduction of brain myelin content upon prolonged endurance exercise

P Ramos-Cabrer, A Cabrera, D Padro… - bioRxiv, 2023 - biorxiv.org
Recent evidence suggests that myelin lipids may act as glial energy reserves when glucose
is lacking, a hypothesis yet to be solidly proven. Hereby, we examined the effects of running …

Data-driven characterization and correction of the orientation dependence of magnetization transfer measures using diffusion MRI

P Karan, M Edde, G Gilbert, M Barakovic, S Magon… - bioRxiv, 2023 - biorxiv.org
Purpose: To characterize the orientation dependence of magnetization transfer (MT)
measures in white matter (WM) and propose a first correction method for such measures …

Myelin water, magnetization transfer, and inhomogeneous magnetization transfer imaging orientation dependence: observations and thoughts

T Joseph - 2023 - open.library.ubc.ca
Previous work has suggested that advanced magnetic resonance imaging (MRI) techniques
for quantifying myelin may be dependent on the orientation of the myelin sheath relative to …

Impact of formalin fixation on multi-compartment T2 relaxation and its tissue orientation dependence in excised pig spinal cord white matter

MC Medina - 2023 - open.library.ubc.ca
In this MRI study, we investigated multi-compartment T₂ relaxation times of fresh, fixed, and
washed pig spinal cord white matter (WM) and their dependence on tissue orientation …

Widespread drastic reduction in brain myelin content upon marathon running

P Ramos-Cabrer, A Cabrera-Zubizarreta, D Padró… - 2023 - researchsquare.com
Recent evidence suggests that myelin lipids may act as glial energy reserves when glucose
is lacking, a hypothesis yet to be solidly proven. Hereby, we examined the effects of running …