[HTML][HTML] Neonatal Exposure to Valproate Induces Long-Term Alterations in Steroid Hormone Levels in the Brain Cortex of Prepubertal Rats

SA Kim, EH Jang, J Lee, SH Cho - International Journal of Molecular …, 2023 - mdpi.com
Valproic acid (VPA) is a known drug for treating epilepsy and mood disorders; however, it is
not recommended for pregnant women because of its possible teratogenicity. VPA affects …

[HTML][HTML] Profiling of adrenal corticosteroids in blood and local tissues of mice during chronic stress

K Vagnerová, M Jágr, C Mekadim, P Ergang… - Scientific Reports, 2023 - nature.com
Stress increases plasma concentrations of corticosteroids, however, their tissue levels are
unclear. Using a repeated social defeat paradigm, we examined the impact of chronic stress …

Effects of neonatal lipopolysaccharide exposure on steroid regulation in the adult mouse brain and blood

H Bajaj - 2024 - open.library.ubc.ca
Early-life infections can have enduring consequences on brain development and function.
Bacterial infections during development increase the risk for neuropsychiatric disorders later …

Inheriting the toxic effects of our ancestors diet: prenatal glyphosate exposure induces colonic inflammation, immune metabolic dysfunction and behavioral deficits in …

JA Barnett - 2024 - open.library.ubc.ca
Glyphosate, commonly known as Roundup®, is heavily used in Canada, with over 50 million
kilograms purchased annually. Its pre-harvest use results in residues in Canadian food …

Effects of lipopolysaccharide on local glucocorticoid regulation in the mouse nervous and immune systems

M Salehzadeh Moghadami - 2024 - open.library.ubc.ca
Immune activation during early development has long-term effects on health, increasing the
risk for neuropsychiatric disorders (eg, mood disorders, schizophrenia, autism) and immune …