Plant-produced vaccines: promise and reality

EP Rybicki - Drug discovery today, 2009 - Elsevier
Plant-produced vaccines are a much-hyped development of the past two decades, whose
time to embrace reality may have finally come. Vaccines have been developed against viral …

Recent advances and safety issues of transgenic plant-derived vaccines

Z Guan, B Guo, Y Huo, Z Guan, J Dai, Y Wei - Applied microbiology and …, 2013 - Springer
Transgenic plant-derived vaccines comprise a new type of bioreactor that combines plant
genetic engineering technology with an organism's immunological response. This …

The last ten years of advancements in plant-derived recombinant vaccines against hepatitis B

YH Joung, SH Park, KB Moon, JH Jeon… - International Journal of …, 2016 - mdpi.com
Disease prevention through vaccination is considered to be the greatest contribution to
public health over the past century. Every year more than 100 million children are …

Expression of GA733‐Fc fusion protein as a vaccine candidate for colorectal cancer in transgenic plants

Z Lu, KJ Lee, Y Shao, JH Lee, Y So… - BioMed Research …, 2012 - Wiley Online Library
The tumor‐associated antigen GA733 is a cell‐surface glycoprotein highly expressed in
colorectal carcinomas. In this study, 3 recombinant genes were constructed as follows …

Plant-based vaccines and cancer therapy: Where are we now and where are we going?

N Rahimian, HR Miraei, A Amiri, MS Ebrahimi… - Pharmacological …, 2021 - Elsevier
Therapeutic vaccines are an effective approach in cancer therapy for treating the disease at
later stages. The Food and Drug Administration (FDA) recently approved the first therapeutic …

[HTML][HTML] Production of recombinant anti-cancer vaccines in plants

JH Lee, K Ko - Biomolecules & Therapeutics, 2017 - ncbi.nlm.nih.gov
Plant expression systems have been developed to produce anti-cancer vaccines. Plants
have several advantages as bioreactors for the production of subunit vaccines: they are …

植物生物反应器表达药用蛋白研究新进展

杜小春, 何正权, 陈磊, 姚伟 - 中国生物工程杂志, 2008 - manu60.magtech.com.cn
植物生物反应器被称为" 分子农田", 它具有无限生产重组蛋白的巨大潜力.
利用转基因植物表达的重组蛋白具备原有的理化性质和生物活性, 从而为人类提供了一种大量 …

Biotechnologically engineered plants

Z Narayanan, BR Glick - Biology, 2023 - mdpi.com
Simple Summary Scientists are exploring the use of new genetic tools to engineer crop
varieties which can result in desirable traits such as improved yield, disease resistance, and …

Plant-made vaccines in the fight against cancer

A Wong-Arce, O González-Ortega… - Trends in …, 2017 - cell.com
Immunotherapies constitute an important trend in developing new cancer treatments, and
several promising candidates are under evaluation in clinical trials. Plants have entered the …

Effect of leaf position and days post-infiltration on transient expression of colorectal cancer vaccine candidate proteins GA733-Fc and GA733-FcK in Nicotiana …

K Kim, YJ Kang, SR Park, DS Kim, SW Lee, K Ko… - PeerJ, 2021 - peerj.com
Immunization with thetumor-associated antigen GA733 glycoprotein, which is highly
expressed in colorectal cancer, is considered to be a promising strategy for cancer …