Dimethyl sulfoxide (DMSO) is an amphipathic molecule widely used as a solvent for water-
insoluble substances, cryopreserving, and cell-biological therapies. It has known properties …

Glaucoma, being asymptomatic for relatively late stage, is recognized as a worldwide cause
of irreversible vision loss. The eye is an impervious organ that exhibits natural anatomical …

Dry eye syndrome (DES) is characterized by decreased tear production and stability,
leading to desiccating stress, inflammation and corneal damage. DES treatment may involve …

It is well known that the cornea plays an important role in providing protection to the eye, but
it is fragile and vulnerable. To clarify the biological effects and molecular mechanisms of the …

Purpose To compare the therapeutic effects of different forms of nintedanib ophthalmic
preparations on neovascularization corneal alkali burns in rats. Methods Forty rat models of …

Congenital aniridia is a rare and severe panocular disease characterized by a complete or
partial iris defect clinically detectable at birth. The most common form of aniridia occurring in …

Peptides are a kind of compounds formed by α-amino acids linked together by peptide
bonds, which are also intermediate products of protein hydrolysis. Nowadays, they mostly …

Background Diabetes poses a risk to diabetic keratopathy in up to two-thirds of patients.
Insulin-degrading enzyme (IDE) is a protease that can break down insulin and several …

Purpose: To compare the inhibitory effects of dovitinib and bevacizumab for treatment of
corneal neovascularization (CNV). Methods: Thirty-nine adult female Sprague Dawley rats …

Understanding the molecular properties of the cell cycle of human pluripotent stem cells
(hPSCs) is critical for effectively promoting differentiation. Here, we use the Fluorescence …