Radiotherapy combined with immunotherapy: the dawn of cancer treatment

Z Zhang, X Liu, D Chen, J Yu - Signal Transduction and Targeted …, 2022 - nature.com
Radiotherapy (RT) is delivered for purposes of local control, but can also exert systemic
effect on remote and non-irradiated tumor deposits, which is called abscopal effect. The view …

PD‐L1 as an emerging target in the treatment and prevention of keratinocytic skin cancer

P Vaishampayan… - Molecular …, 2023 - Wiley Online Library
Recent advances in the understanding and targeting of immune checkpoints have led to
great progress in immune therapies against many forms of cancer. While many types of …

A novel radiotherapeutic approach to treat bulky metastases even from cutaneous squamous cell carcinoma: its rationale and a look at the reliability of the linear …

G Ferini, P Castorina, V Valenti, SI Illari… - Frontiers in …, 2022 - frontiersin.org
Introduction Metastatic cutaneous squamous cell carcinoma (cSCC) is a very rare condition.
The lack of definition of an oligometastatic subgroup means that there is no consensus for its …

Overexpression of CCL-20 and CXCL-8 genes enhances tumor escape and resistance to cemiplimab, a programmed cell death protein-1 (PD-1) inhibitor, in patients …

V De Falco, S Napolitano, R Franco… - …, 2024 - Taylor & Francis
Cemiplimab has demonstrated relevant clinical activity in cutaneous squamous cell
carcinoma (cSCC) but mechanisms of primary and acquired resistance to immunotherapy …

The next chapter in immunotherapy and radiation combination therapy–cancer-specific perspectives

AJ Wisdom, CA Barker, JY Chang, S Demaria… - International Journal of …, 2024 - Elsevier
Immunotherapeutic agents have revolutionized cancer treatment over the past decade.
However, most patients fail to respond to immunotherapy alone. A growing body of …

The role of radiation therapy in the treatment of non-melanoma skin cancer

E Yosefof, N Kurman, D Yaniv - Cancers, 2023 - mdpi.com
Simple Summary While surgery remains the main treatment modality for non-melanoma skin
cancer (NMSC), radiotherapy still plays a major role in the treatment algorithm, even with the …

Therapeutic cancer vaccines for nonmelanoma skin cancer

SE Wu, YH Chen, CT Hung, BH Yang - Current Treatment Options in …, 2023 - Springer
Opinion statement The development of immunotherapies for nonmelanoma skin cancer
(NMSC) has lagged far behind that for melanoma in the past few decades, given that the …

Scientific research directions on the histopathology and immunohistochemistry of the cutaneous squamous cell carcinoma: A scientometric study

IG Cocuz, ME Cocuz, A Repanovici, AH Sabău… - Medicina, 2022 - mdpi.com
Introduction: Cutaneous squamous cell carcinoma (cSCC) is one of the most frequently
occurring types of cancer in humans. Scientometric research is an innovative method for …

Evaluation of Short‐Term Efficacy of PD‐1 Monoclonal Antibody Immunotherapy for Lymphoma by Positron Emission Tomography/Computed Tomography Imaging …

J Fang, Z Chen - Contrast Media & Molecular Imaging, 2022 - Wiley Online Library
The objective of this study was to investigate the value of PET/CT imaging based on CNN
image registration algorithm in evaluating the short‐term efficacy of PD‐1 monoclonal …

Anti-PD-1 for the treatment of advanced cutaneous squamous cell carcinoma in elderly patients: a French multicenter retrospective survey

Q Samaran, R Samaran, E Ferreira, N Haddad… - Journal of Cancer …, 2023 - Springer
Background Anti-PD1 agents are currently recommended as first-line treatment in advanced
cutaneous squamous cell carcinoma (acSCC) by updated European guidelines. Although …