Successful establishment of infection by bacterial pathogens requires adhesion to host cells,
colonization of tissues, and in certain cases, cellular invasion—followed by intracellular …

The chaperone–usher (CU) pathway of pilus biogenesis is the most widespread of the five
pathways that assemble adhesive pili at the surface of Gram-negative bacteria. Recent …

Many Proteobacteria use the chaperone/usher pathway to assemble proteinaceous
filaments on the bacterial surface. These filaments can curl into fimbrial or nonfimbrial …

Over the last few years, dramatic increases in our knowledge about diffusely adhering
Escherichia coli (DAEC) pathogenesis have taken place. The typical class of DAEC includes …

Entry into host cells is required for many bacterial pathogens to effectively disseminate
within a host, avoid immune detection and cause disease. In recent years, many ostensibly …

The pathogenicity and clinical pertinence of diffusely adhering Escherichia coli expressing
the Afa/Dr adhesins (Afa/Dr DAEC) in urinary tract infections (UTIs) and pregnancy …

Gram-negative bacteria express a wide variety of organelles on their cell surface. These
surface structures may be the end products of secretion systems, such as the hair-like fibers …

The presence of a diversity of virulence factors such as Chaperone-Usher (CU) fibers in
uropathogenic Escherichia coli (UPEC) pathotypes virulome has offered these bacteria a …

The immunoglobulin (Ig) protein domain is widespread in nature having a well-recognized
role in proteins of the immune system. In this review, we describe the proteins containing Ig …

Abstract Background Uropathogenic Escherichia coli (UPEC) cause urinary tract infections
(UTIs) in approximately 50% of women. These bacteria use type 1 and P pili for host …