In Vivo Bioluminescent Imaging (BLI): Noninvasive Visualization and Interrogation of Biological Processes in Living Animals

DM Close, T Xu, GS Sayler, S Ripp - Sensors, 2010 - mdpi.com
In vivo bioluminescent imaging (BLI) is increasingly being utilized as a method for modern
biological research. This process, which involves the noninvasive interrogation of living …

Targeted cancer immunotherapy with genetically engineered oncolytic Salmonella typhimurium

Y Guo, Y Chen, X Liu, JJ Min, W Tan, JH Zheng - Cancer letters, 2020 - Elsevier
Conventional chemotherapies have some limitations, including the lack of selectivity, high
toxicity to normal tissues, multidrug resistance, and tumor relapse. Recently, great progress …

[HTML][HTML] Salmonella-mediated cancer therapy: an innovative therapeutic strategy

Z Mi, ZC Feng, C Li, X Yang, MT Ma, PF Rong - Journal of Cancer, 2019 - ncbi.nlm.nih.gov
Bacterial-mediated cancer therapy (BMCT) has become a hot topic in the area of antitumor
treatment. Salmonella has been recommended to specifically colonize and proliferate inside …

Bacterial Drug Delivery Systems for Cancer Therapy:“Why” and “How”

X Zhao, N Xie, H Zhang, W Zhou, J Ding - Pharmaceutics, 2023 - mdpi.com
Cancer is one of the major diseases that endanger human health. However, the use of
anticancer drugs is accompanied by a series of side effects. Suitable drug delivery systems …

The diversity of microbial responses to nitric oxide and agents of nitrosative stress: close cousins but not identical twins

LAH Bowman, S McLean, RK Poole… - Advances in microbial …, 2011 - Elsevier
Nitric oxide and related nitrogen species (reactive nitrogen species) now occupy a central
position in contemporary medicine, physiology, biochemistry, and microbiology. In particular …

Recombinant Attenuated Salmonella enterica as a Delivery System of Heterologous Molecules in Cancer Therapy

EI Becerra-Báez, SE Meza-Toledo, P Muñoz-López… - Cancers, 2022 - mdpi.com
Simple Summary Cancer is among the main causes of death of millions of individuals
worldwide. Although survival has improved with conventional treatments, the appearance of …

Integration of Salmonella into Combination Cancer Therapy

BH Al-Saafeen, MJ Fernandez-Cabezudo… - Cancers, 2021 - mdpi.com
Simple Summary Despite significant advances in the development of new treatments,
cancer continues to be a major public health concern due to the high mortality associated …

Bacterial-directed enzyme prodrug therapy

P Lehouritis, C Springer, M Tangney - Journal of Controlled Release, 2013 - Elsevier
Current conventional treatments for cancer lack tumour selectivity resulting in the destruction
of healthy tissue and severe adverse effects to the patient in addition to limiting the …

Cancer Immunotherapy: Priming the Host Immune Response with Live Attenuated Salmonella enterica

MA Hernández-Luna… - Journal of Immunology …, 2018 - Wiley Online Library
In recent years, cancer immunotherapy has undergone great advances because of our
understanding of the immune response and the mechanisms through which tumor cells …

Perspectives on Oncolytic Salmonella in Cancer Immunotherapy—A Promising Strategy

D Wang, X Wei, DV Kalvakolanu, B Guo… - Frontiers in …, 2021 - frontiersin.org
Since the first reported spontaneous regression of tumors in patients with streptococcus
infection, cancer biological therapy was born and it evolved into today's immunotherapy over …