Red blood cell (RBC) transfusion is common in critically ill, postsurgical, and posttrauma
patients in whom both systemic inflammation and immune suppression are associated with …

Transfusion‐related immunomodulation (TRIM) in the intensive care unit (ICU) is difficult to
define and likely represents a complicated set of physiologic responses to transfusion …

Objective To summarize current understanding of the mechanisms responsible for changes
occurring during red blood cell (RBC) storage, collectively known as the storage lesion, and …

Importance There are conflicting data on the association between blood donor
characteristics and outcomes among patients receiving transfusions. Objective To evaluate …

BACKGROUND The risk of developing red blood cell (RBC) transfusion–associated
necrotizing enterocolitis (TANEC) in preterm infants has recently been emphasized. Our aim …

Pre‐term infants have one of the highest transfusion requirements within the hospital‐
setting. The vast majority of blood transfusions performed in Neonatal Intensive Care Units …

Transfusion-related acute lung injury (TRALI) is one of the leading causes of transfusion-
related fatalities and, to date, is without available therapies. Here, we investigated the role of …

Anaemia of prematurity will affect 90% of all very preterm infants, resulting in at least one red
blood cell (RBC) transfusion. A significant proportion of preterm infants require multiple …

Background and Objectives Studies in mice suggest that rapid transfusions of red blood
cells (RBC s), refrigerator stored for longer durations, induce a pro‐inflammatory cytokine …

Background Previous reports describe a statistical association, among very‐low‐birthweight
(VLBW,< 1500 g) neonates, between red blood cell (RBC) transfusion in the first days after …