Next generation sequencing and bioinformatics methodologies for infectious disease research and public health: approaches, applications, and considerations for …
I Maljkovic Berry, MC Melendrez… - The Journal of …, 2020 - academic.oup.com
Next generation sequencing (NGS) combined with bioinformatics has successfully been
used in a vast array of analyses for infectious disease research of public health relevance …
used in a vast array of analyses for infectious disease research of public health relevance …
Emerging and reemerging neglected tropical diseases: a review of key characteristics, risk factors, and the policy and innovation environment
In global health, critical challenges have arisen from infectious diseases, including the
emergence and reemergence of old and new infectious diseases. Emergence and …
emergence and reemergence of old and new infectious diseases. Emergence and …
Between a bug and a hard place: Trypanosoma cruzi genetic diversity and the clinical outcomes of Chagas disease
LA Messenger, MA Miles, C Bern - Expert review of anti-infective …, 2015 - Taylor & Francis
Over the last 30 years, concomitant with successful transnational disease control programs
across Latin America, Chagas disease has expanded from a neglected, endemic parasitic …
across Latin America, Chagas disease has expanded from a neglected, endemic parasitic …
Recent advances in trypanosomatid research: genome organization, expression, metabolism, taxonomy and evolution
Unicellular flagellates of the family Trypanosomatidae are obligatory parasites of
invertebrates, vertebrates and plants. Dixenous species are aetiological agents of a number …
invertebrates, vertebrates and plants. Dixenous species are aetiological agents of a number …
Next generation sequencing: implications in personalized medicine and pharmacogenomics
B Rabbani, H Nakaoka, S Akhondzadeh… - Molecular …, 2016 - pubs.rsc.org
A breakthrough in next generation sequencing (NGS) in the last decade provided an
unprecedented opportunity to investigate genetic variations in humans and their roles in …
unprecedented opportunity to investigate genetic variations in humans and their roles in …
Hybridization in parasites: consequences for adaptive evolution, pathogenesis, and public health in a changing world
Hybridization of parasites is an emerging public health concern at the interface of infectious
disease biology and evolution. Increasing economic development, human migration, global …
disease biology and evolution. Increasing economic development, human migration, global …
Pathogenicity and virulence of African trypanosomes: From laboratory models to clinically relevant hosts
LJ Morrison, PC Steketee, MD Tettey, KR Matthews - Virulence, 2023 - Taylor & Francis
African trypanosomes are vector-borne protozoa, which cause significant human and animal
disease across sub-Saharan Africa, and animal disease across Asia and South America. In …
disease across sub-Saharan Africa, and animal disease across Asia and South America. In …
Population genomics reveals the origin and asexual evolution of human infective trypanosomes
Evolutionary theory predicts that the lack of recombination and chromosomal re-assortment
in strictly asexual organisms results in homologous chromosomes irreversibly accumulating …
in strictly asexual organisms results in homologous chromosomes irreversibly accumulating …
Colonization and genetic diversification processes of Leishmania infantum in the Americas
Leishmania infantum causes visceral leishmaniasis, a deadly vector-borne disease
introduced to the Americas during the colonial era. This non-native trypanosomatid parasite …
introduced to the Americas during the colonial era. This non-native trypanosomatid parasite …
Admixture in Humans of Two Divergent Plasmodium knowlesi Populations Associated with Different Macaque Host Species
Human malaria parasite species were originally acquired from other primate hosts and
subsequently became endemic, then spread throughout large parts of the world. A major …
subsequently became endemic, then spread throughout large parts of the world. A major …