Ubiquitous yet unique, lipid droplets are intracellular organelles that are increasingly being
recognized for their versatility beyond energy storage. Advances uncovering the intricacies …

Lipid droplets (LDs) are ubiquitous organelles that store neutral lipids for energy or
membrane synthesis and act as hubs for metabolic processes. Cells generate LDs de novo …

Hepatic glucose release into the circulation is vital for brain function and survival during
periods of fasting and is modulated by an array of hormones that precisely regulate plasma …

Lipid droplets are the universal cellular organelles for the transient or long-term storage of
lipids. The number, size and composition of lipid droplets vary greatly within cells in a …

Seipin is an oligomeric integral endoplasmic reticulum (ER) protein involved in lipid droplet
(LD) biogenesis. To study the role of seipin in LD formation, we relocalized it to the nuclear …

Lipid droplets (LDs) are multi-functional cellular organelles that store energy, and regulate
many aspects of cell physiology. However, our understanding of the biogenesis of LDs …

Congenital generalized lipodystrophy (CGL) is a heterogeneous autosomal recessive
disorder characterized by a near complete lack of adipose tissue from birth and, later in life …

The compartmentation of neutral lipids in plants is mostly associated with seed tissues,
where triacylglycerols (TAGs) stored within lipid droplets (LDs) serve as an essential …

Lipid droplets (LDs) are important cellular organelles that govern the storage and turnover of
lipids. Little is known about how the size of LDs is controlled, although LDs of diverse sizes …

Human voluntary movement is controlled by the pyramidal motor system, a long CNS
pathway comprising corticospinal and lower motor neurons. Hereditary spastic paraplegias …