E-type prostanoid receptor 4 drives resolution of intestinal inflammation by blocking epithelial necroptosis
JV Patankar, TM Müller, S Kantham, MG Acera… - Nature cell …, 2021 - nature.com
Inflammatory bowel diseases present with elevated levels of intestinal epithelial cell (IEC)
death, which compromises the gut barrier, activating immune cells and triggering more IEC …
death, which compromises the gut barrier, activating immune cells and triggering more IEC …
CD137L-DCs, potent immune-stimulators—history, characteristics, and perspectives
Dendritic cell (DC)-based immunotherapies are being explored for over 20 years and found
to be very safe. Most often, granulocyte-macrophage colony-stimulating factor (GM-CSF) …
to be very safe. Most often, granulocyte-macrophage colony-stimulating factor (GM-CSF) …
CD137 ligand activated microglia induces oligodendrocyte apoptosis via reactive oxygen species
YA Yeo, JM Martínez Gómez, JL Croxford… - Journal of …, 2012 - Springer
Abstract CD137 (4-1BB, TNFRSF9), a member of the tumor necrosis factor (TNF) receptor
family, is a potent T cell co-stimulatory molecule. CD137 ligand (CD137L) is expressed by …
family, is a potent T cell co-stimulatory molecule. CD137 ligand (CD137L) is expressed by …
CD137L-stimulated dendritic cells are more potent than conventional dendritic cells at eliciting cytotoxic T-cell responses
Z Harfuddin, S Kwajah, A Chong Nyi Sim… - …, 2013 - Taylor & Francis
Dendritic cells (DCs) are highly potent initiators of adaptive immune responses and, as such,
represent promising tools for immunotherapeutic applications. Despite their potential, the …
represent promising tools for immunotherapeutic applications. Despite their potential, the …
Recombinant TAT-CD137 ligand cytoplasmic domain fusion protein induces the production of IL-6 and TNF-α in peritoneal macrophages
JD Kim, EA Lee, NN Quang, HR Cho… - Immune …, 2011 - synapse.koreamed.org
Background The ligand for CD137 (CD137L; also called 4-1BBL) is mainly expressed on
activated APCs such as dendritic cells, B cells and macrophages. Even though CD137L …
activated APCs such as dendritic cells, B cells and macrophages. Even though CD137L …
Regulation of myelopoiesis by CD137L signaling
Q Tang, D Jiang, Z Harfuddin, K Cheng… - International Reviews …, 2014 - Taylor & Francis
CD137 ligand (CD137L) has emerged as a powerful regulator of myelopoiesis that links
emergency situations, such as infections, to the generation of additional myeloid cells, and …
emergency situations, such as infections, to the generation of additional myeloid cells, and …
[PDF][PDF] Role of CD137-CD137L interaction in microglia-mediated immune response
NURSB ABDULLAH - 2016 - core.ac.uk
In today's ageing populations, the incidence of age-related neurodegenerative diseases is
on the rise. More often than not, activated microglia are implicated in the pathogenesis of …
on the rise. More often than not, activated microglia are implicated in the pathogenesis of …
[PDF][PDF] An investigation of CD137 and CD137 ligand activities on murine microglia
Y Yee - National University Of Singapore, 2013 - core.ac.uk
Firstly, I would like to thank the Department of Physiology and the Immunology Program (IP)
of NUS, for the provision of all laboratory facilities and equipment. I would also like to …
of NUS, for the provision of all laboratory facilities and equipment. I would also like to …
[PDF][PDF] CHARACTERISATION OF THE ANTI-VIRAL T-CELL RESPONSE INDUCED BY HUMAN CD137 LIGAND DENDRITIC CELLS
Z HARFUDDIN - 2013 - core.ac.uk
I would like to express my heartfelt gratitude towards Associate Professor Herbert Schwarz
for his invaluable guidance and suggestions throughout the course of this project. I am truly …
for his invaluable guidance and suggestions throughout the course of this project. I am truly …