Revisiting the virulence hallmarks of Pseudomonas aeruginosa: a chronicle through the perspective of quorum sensing
Pseudomonas aeruginosa is an opportunistic pathogen and the leading cause of mortality
among immunocompromised patients in clinical setups. The hallmarks of virulence in P …
among immunocompromised patients in clinical setups. The hallmarks of virulence in P …
Galleria mellonella infection models for the study of bacterial diseases and for antimicrobial drug testing
CJY Tsai, JMS Loh, T Proft - Virulence, 2016 - Taylor & Francis
abstract Galleria mellonella (greater wax moth or honeycomb moth) has been introduced as
an alternative model to study microbial infections. G. mellonella larvae can be easily and …
an alternative model to study microbial infections. G. mellonella larvae can be easily and …
From in vitro to in vivo Models of Bacterial Biofilm-Related Infections
The influence of microorganisms growing as sessile communities in a large number of
human infections has been extensively studied and recognized for 30–40 years, therefore …
human infections has been extensively studied and recognized for 30–40 years, therefore …
Light-activated molecular machines are fast-acting broad-spectrum antibacterials that target the membrane
The increasing occurrence of antibiotic-resistant bacteria and the dwindling antibiotic
research and development pipeline have created a pressing global health crisis. Here, we …
research and development pipeline have created a pressing global health crisis. Here, we …
Innate humoral immune defences in mammals and insects: The same, with differences?
G Sheehan, A Garvey, M Croke, K Kavanagh - Virulence, 2018 - Taylor & Francis
The insect immune response demonstrates many similarities to the innate immune response
of mammals and a wide range of insects is now employed to assess the virulence of …
of mammals and a wide range of insects is now employed to assess the virulence of …
The environmental occurrence of Pseudomonas aeruginosa
Pseudomonas aeruginosa is generally described as ubiquitous in natural settings, such as
soil and water. However, because anecdotal observations and published reports have …
soil and water. However, because anecdotal observations and published reports have …
Understanding biofilm resistance to antibacterial agents
D Davies - Nature reviews Drug discovery, 2003 - nature.com
According to a public announcement by the US National Institutes of Health,“Biofilms are
medically important, accounting for over 80% of microbial infections in the body”. Yet …
medically important, accounting for over 80% of microbial infections in the body”. Yet …
Quinolones: from antibiotics to autoinducers
S Heeb, MP Fletcher, SR Chhabra… - FEMS microbiology …, 2011 - academic.oup.com
Since quinine was first isolated, animals, plants and microorganisms producing a wide
variety of quinolone compounds have been discovered, several of which possess …
variety of quinolone compounds have been discovered, several of which possess …
Novel Strategies for the Treatment of Pseudomonas aeruginosa Infections
S Wagner, R Sommer, S Hinsberger, C Lu… - Journal of medicinal …, 2016 - ACS Publications
Infections with Pseudomonas aeruginosa have become a concerning threat in hospital-
acquired infections and for cystic fibrosis patients. The major problem leading to high …
acquired infections and for cystic fibrosis patients. The major problem leading to high …
Repurposing phytochemicals as anti‐virulent agents to attenuate quorum sensing‐regulated virulence factors and biofilm formation in Pseudomonas aeruginosa
Unregulated consumption and overexploitation of antibiotics have paved the way for
emergence of antibiotic‐resistant strains and 'superbugs'. Pseudomonas aeruginosa is …
emergence of antibiotic‐resistant strains and 'superbugs'. Pseudomonas aeruginosa is …