Apoptotic mechanisms of quercetin in liver cancer: recent trends and advancements

G Sethi, P Rath, A Chauhan, A Ranjan, R Choudhary… - Pharmaceutics, 2023 - mdpi.com
Due to rising incidence rates of liver cancer and worries about the toxicity of current
chemotherapeutic medicines, the hunt for further alternative methods to treat this malignancy …

Pharmacological aspects of natural quercetin in rheumatoid arthritis

M Tang, Y Zeng, W Peng, X Xie, Y Yang… - Drug Design …, 2023 - Taylor & Francis
Rheumatoid arthritis (RA) is a chronic autoimmune disease that can lead to severe joint
damage, disability and mortality. Quercetin (QUE) is a natural flavonoid that is ubiquitous in …

Effects of sorafenib and quercetin alone or in combination in treating hepatocellular carcinoma: in vitro and in vivo approaches

S Abdu, N Juaid, A Amin, M Moulay, N Miled - Molecules, 2022 - mdpi.com
Sorafenib is the first drug approved to treat advanced hepatocellular carcinoma (HCC) and
continues as the gold-standard therapy against HCC. However, acquired drug resistance …

Quercetin promotes osteogenic differentiation and antioxidant responses of mouse bone mesenchymal stem cells through activation of the AMPK/SIRT1 signaling …

N Wang, L Wang, J Yang, Z Wang… - Phytotherapy …, 2021 - Wiley Online Library
Decrepitude and apoptosis of bone mesenchymal stem cells (BMSCs) induced by reactive
oxygen species (ROS) lead to inhibited osteogenic differentiation, causing decreased bone …

Quercetin as a protective agent for liver diseases: A comprehensive descriptive review of the molecular mechanism

X Zhao, J Wang, Y Deng, L Liao, M Zhou… - Phytotherapy …, 2021 - Wiley Online Library
Quercetin is the major representative of the flavonoid subgroup of flavones, with good
pharmacological activities for the treatment of liver diseases, including liver steatosis, fatty …

Quercetin and non-alcoholic fatty liver disease: A review based on experimental data and bioinformatic analysis

L Chen, J Liu, G Mei, H Chen, S Peng, Y Zhao… - Food and Chemical …, 2021 - Elsevier
Quercetin, a polyphenol widely present in the plant kingdom, has received great interest due
to pleiotropic effects. As evidenced by animal and cellular studies, quercetin exerts …

Antiangiogenic phytochemicals constituent of diet as promising candidates for chemoprevention of cancer

AD Marrero, AR Quesada, B Martínez-Poveda… - Antioxidants, 2022 - mdpi.com
Despite the extensive knowledge on cancer nature acquired over the last years, the high
incidence of this disease evidences a need for new approaches that complement the clinical …

Efficacy and safety of dietary polyphenols in rheumatoid arthritis: A systematic review and meta-analysis of 47 randomized controlled trials

Z Long, W Xiang, Q He, W Xiao, H Wei, H Li… - Frontiers in …, 2023 - frontiersin.org
Objective To evaluate safety and efficacy of dietary polyphenols in the treatment of
rheumatoid arthritis (RA). Methods CNKI, Pubmed, Cochrane library, Embase were …

Cogent role of flavonoids as key orchestrators of chemoprevention of hepatocellular carcinoma: A review

J Baby, AR Devan, AR Kumar… - Journal of Food …, 2021 - Wiley Online Library
Chemopreventive approaches with food‐derived phytochemicals are progressively rising as
a significant aspect of tumor management and control. Herein, we have showcased the …

Delivery of natural agents by means of mesoporous silica nanospheres as a promising anticancer strategy

K AbouAitah, W Lojkowski - Pharmaceutics, 2021 - mdpi.com
Natural prodrugs derived from different natural origins (eg, medicinal plants, microbes,
animals) have a long history in traditional medicine. They exhibit a broad range of …