Synthetic extracellular matrices with function-encoding peptides
The communication of cells with their surroundings is mostly encoded in the epitopes of
structural and signalling proteins present in the extracellular matrix (ECM). These peptide …
structural and signalling proteins present in the extracellular matrix (ECM). These peptide …
Peptide hydrogels and nanostructures controlling biological machinery
J Mitrovic, G Richey, S Kim, MO Guler - Langmuir, 2023 - ACS Publications
Peptides are versatile building blocks for the fabrication of various nanostructures that result
in the formation of hydrogels and nanoparticles. Precise chemical functionalization promotes …
in the formation of hydrogels and nanoparticles. Precise chemical functionalization promotes …
Transformable nano-antibiotics for mechanotherapy and immune activation against drug-resistant Gram-negative bacteria
The dearth of antibiotic candidates against Gram-negative bacteria and the rise of antibiotic
resistance create a global health concern. The challenge lies in the unique Gram-negative …
resistance create a global health concern. The challenge lies in the unique Gram-negative …
TLR9 and COVID-19: a multidisciplinary theory of a multifaceted therapeutic target
GFG Bezemer, J Garssen - Frontiers in Pharmacology, 2021 - frontiersin.org
By mapping the clinical pathophysiology of the novel coronavirus disease 2019 (COVID-19)
against insights from virology, immunology, genomics, epidemiology and pharmacology, it is …
against insights from virology, immunology, genomics, epidemiology and pharmacology, it is …
[HTML][HTML] Peptide-based supramolecular vaccine systems
Currently approved replication-competent and inactivated vaccines are limited by excessive
reactogenicity and poor safety profiles, while subunit vaccines are often insufficiently …
reactogenicity and poor safety profiles, while subunit vaccines are often insufficiently …
Therapeutic synthetic and natural materials for immunoengineering
Immunoengineering is a rapidly evolving field that has been driving innovations in
manipulating immune system for new treatment tools and methods. The need for materials …
manipulating immune system for new treatment tools and methods. The need for materials …
Nanohydroxyapatite-Loaded, Self-Assembled Peptide Gels for Antibacterial and Osteogenic Activities
Bone constitutes the primary component of the skeletal system, and a substantial reduction
in bone density can occur due to trauma, aging, infections, and illnesses. Infections often …
in bone density can occur due to trauma, aging, infections, and illnesses. Infections often …
Therapeutic vaccines for cancer immunotherapy
J Wang, M Mamuti, H Wang - ACS Biomaterials Science & …, 2020 - ACS Publications
The rapid development of nanobiotechnology has enabled progress in therapeutic cancer
vaccines. These vaccines stimulate the host innate immune response by tumor antigens …
vaccines. These vaccines stimulate the host innate immune response by tumor antigens …
Functionalized prion-inspired amyloids for biosensor applications
Protein amyloid nanofibers provide a biocompatible platform for the development of
functional nanomaterials. However, the functionalities generated up to date are still limited …
functional nanomaterials. However, the functionalities generated up to date are still limited …