Synthetic extracellular matrices with function-encoding peptides

C Ligorio, A Mata - Nature reviews bioengineering, 2023 - nature.com
The communication of cells with their surroundings is mostly encoded in the epitopes of
structural and signalling proteins present in the extracellular matrix (ECM). These peptide …

Peptide hydrogels and nanostructures controlling biological machinery

J Mitrovic, G Richey, S Kim, MO Guler - Langmuir, 2023 - ACS Publications
Peptides are versatile building blocks for the fabrication of various nanostructures that result
in the formation of hydrogels and nanoparticles. Precise chemical functionalization promotes …

Transformable nano-antibiotics for mechanotherapy and immune activation against drug-resistant Gram-negative bacteria

RS Li, J Liu, C Wen, Y Shi, J Ling, Q Cao, L Wang… - Science …, 2023 - science.org
The dearth of antibiotic candidates against Gram-negative bacteria and the rise of antibiotic
resistance create a global health concern. The challenge lies in the unique Gram-negative …

TLR9 and COVID-19: a multidisciplinary theory of a multifaceted therapeutic target

GFG Bezemer, J Garssen - Frontiers in Pharmacology, 2021 - frontiersin.org
By mapping the clinical pathophysiology of the novel coronavirus disease 2019 (COVID-19)
against insights from virology, immunology, genomics, epidemiology and pharmacology, it is …

[HTML][HTML] Peptide-based supramolecular vaccine systems

CL O'Neill, PC Shrimali, ZE Clapacs, MA Files… - Acta biomaterialia, 2021 - Elsevier
Currently approved replication-competent and inactivated vaccines are limited by excessive
reactogenicity and poor safety profiles, while subunit vaccines are often insufficiently …

Therapeutic synthetic and natural materials for immunoengineering

A Slezak, K Chang, S Hossainy, A Mansurov… - Chemical Society …, 2024 - pubs.rsc.org
Immunoengineering is a rapidly evolving field that has been driving innovations in
manipulating immune system for new treatment tools and methods. The need for materials …

Peptide Assemblies for Cancer Therapy

Y Qiao, B Xu - ChemMedChem, 2023 - Wiley Online Library
Supramolecular assemblies made by the self‐assembly of peptides are finding an
increasing number of applications in various fields. While the early exploration of peptide …

Nanohydroxyapatite-Loaded, Self-Assembled Peptide Gels for Antibacterial and Osteogenic Activities

P Bundel, V Chawla, AJ Saikia… - ACS Applied Nano …, 2024 - ACS Publications
Bone constitutes the primary component of the skeletal system, and a substantial reduction
in bone density can occur due to trauma, aging, infections, and illnesses. Infections often …

Therapeutic vaccines for cancer immunotherapy

J Wang, M Mamuti, H Wang - ACS Biomaterials Science & …, 2020 - ACS Publications
The rapid development of nanobiotechnology has enabled progress in therapeutic cancer
vaccines. These vaccines stimulate the host innate immune response by tumor antigens …

Functionalized prion-inspired amyloids for biosensor applications

M Díaz-Caballero, S Navarro, S Ventura - Biomacromolecules, 2021 - ACS Publications
Protein amyloid nanofibers provide a biocompatible platform for the development of
functional nanomaterials. However, the functionalities generated up to date are still limited …