Background Globally, children under 15 years represent approximately 12% of new
tuberculosis cases, but 16% of the estimated 1.4 million deaths. This higher share of …

The successful care of children and adolescents with TB requires a recognition of the risk
factors and clinical and radiographic signs of TB, especially when microbiologic testing is …

Lipoarabinomannan (LAM) is a prospective noninvasive biomarker for tuberculosis (TB)
diagnosis. Here, we report a visual immunoassay of high sensitivity for detecting LAM in …

Background Post-tuberculosis (post-TB) lung disease is an under-recognised consequence
of pulmonary tuberculosis (pTB). We aimed to estimate the prevalence of residual lung …

There is no microbiological gold standard for childhood tuberculosis (TB) diagnosis. The
paucibacillary nature of the disease, challenges in sample collection in young children, and …

Introduction With growing attention globally to the childhood tuberculosis epidemic after
decades of neglect, and with the burden of severe acute malnutrition (SAM) remaining …

Background Tuberculosis (TB) is a global burden, and this is likely to remain the case due to
a lack of adequate and accurate point-of-care diagnostic tests. Obtaining good-quality …

In childhood tuberculosis (TB), with an estimated 69% of missed cases in children under 5
years of age, the case detection gap is larger than in other age groups, mainly due to its …

Background: Timely and accurate diagnosis of tuberculosis (TB) remains a major challenge.
Lipoarabinomannan (LAM) is a specific component of the cell envelope of Mycobacterium …

Over 1 million children develop tuberculosis (TB) each year, with a quarter dying. Multiple
factors impact the risk of a child being exposed to Mycobacterium tuberculosis (Mtb), the risk …