The onset of multiple sclerosis (MS) in childhood poses diagnostic and therapeutic
challenges, particularly if the symptoms of the first demyelinating event resemble acute …

Pediatric multiple sclerosis (MS) accounts for up to 5% of all MS cases. Work conducted over
the past 5 years has provided new information about the treatment, pathogenesis …

Background The course and prognosis of childhood-onset multiple sclerosis have not been
well described. Methods We used data from 13 adult neurology departments affiliated with …

Objective: To evaluate the clinical course of MS in individuals with onset of MS before age
16. Methods: Patients with onset of MS before age 16 (n= 116) with complete clinical …

Background The full spectrum of clinical manifestations and outcome, and the potential
importance of regional or demographic features or viral triggers in paediatric multiple …

Fifty-four subjects (36 females and 18 males) affected by clinically definite multiple sclerosis
(MS) and with onset of the disease at 15 years of age or before were prospectively studied in …

Objectives: To characterize MS patients with the earliest onset of disease. Background: MS—
primarily a disease of young adulthood—begins in childhood in 3 to 5% of cases. However …

There is increasing appreciation that multiple sclerosis (MS) can begin in childhood or
adolescence, but pediatric MS continues to be a rare entity, with an estimated 2 to 5% of …

Background: This survey was planned to study the prevalence and incidence of multiple
sclerosis (MS) in Isfahan, Iran and to describe the clinical features of MS in general and in …

Multiple sclerosis (MS) is traditionally the domain of adult neurologists due to its
characteristic presentation during early adult life. Although descriptions of infants with MS …