Bicelles and nanodiscs for biophysical chemistry

EJ Dufourc - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2021 - Elsevier
Membrane nanoobjects are very important tools to study biomembrane properties. Two
types are described herein: Bicelles and Nanodiscs. Bicelles are obtained by thorough …

Exploring non-equilibrium processes and spatio-temporal scaling laws in heated egg yolk using coherent X-rays

ND Anthuparambil, A Girelli, S Timmermann… - Nature …, 2023 - nature.com
The soft-grainy microstructure of cooked egg yolk is the result of a series of out-of-
equilibrium processes of its protein-lipid contents; however, it is unclear how egg yolk …

Delivery of RNA to the Blood-Brain Barrier Endothelium Using Cationic Bicelles

J Cheng, L Wang, V Guttha, G Haugstad… - Pharmaceutics, 2023 - mdpi.com
Blood-brain barrier (BBB) dysfunction is prevalent in Alzheimer's disease and other
neurological disorders. Restoring normal BBB function through RNA therapy is a potential …

Codelivery of paclitaxel and parthenolide in discoidal bicelles for a synergistic anticancer effect: structure matters

AT Rad, D Hargrove, L Daneshmandi… - Advanced …, 2022 - Wiley Online Library
Nanotechnology has long been used to improve the tumor targeting of chemotherapeutics.
The structure of these nanocarriers greatly affects their efficacy and toxicity. Herein …

[HTML][HTML] The effects of temperature, salinity, concentration and PEGylated lipid on the spontaneous nanostructures of bicellar mixtures

Y Liu, M Li, Y Yang, Y Xia, MP Nieh - Biochimica et Biophysica Acta (BBA) …, 2014 - Elsevier
The self-assembling morphologies of low-concentration (mostly 1 and 10 mg/mL) bicellar
mixtures composed of zwitterionic dipalmitoyl (di-C 16) phosphatidylcholine (DPPC) …

A universal discoidal nanoplatform for the intracellular delivery of PNAs

AT Rad, S Malik, L Yang, TK Oberoi-Khanuja, MP Nieh… - Nanoscale, 2019 - pubs.rsc.org
Peptide nucleic acids (PNAs) have gained considerable attention due to their remarkable
potential in gene editing and targeting-based strategies. However, cellular delivery of PNAs …

Structural transition in aqueous lipid/bile salt [DPPC/NaDC] supramolecular aggregates: SANS and DLS study

MA Kiselev, M Janich, A Hildebrand, P Strunz… - Chemical Physics, 2013 - Elsevier
Small angle neutron scattering (SANS) and dynamic light scattering (DLS) were used to
study different aggregation states in sodium deoxycholate (NaDC)-phosphatidylcholine …

Impact of Ionic Liquids on the Physicochemical Behavior of Vesicles

E Manna, M Barai, MK Mandal, H Sultana… - The Journal of …, 2024 - ACS Publications
The effects of two ionic liquids (ILs), 1-butyl-3-methylimidazolium tetrafluoroborate ([bmim]
BF4) and 1-butyl-1-methyl pyrrolidinium tetrafluoroborate ([bmp] BF4), on a mixture of …

Packing DNA with disc-shaped bicelles

PW Yang, TL Lin, TY Lin, CH Yang, Y Hu, US Jeng - Soft Matter, 2013 - pubs.rsc.org
Cationic lipid–DNA (CL–DNA) complexes can be used as non-viral vectors to improve
transfection efficiency in gene therapy. It is greatly desirable to develop new ways of packing …

Highly reversible & ultra-sensitive FRET-based temperature detection using pyrene-coumarin 102-loaded hybrid niosome

R Lazarus, A Nag - Journal of Molecular Liquids, 2024 - Elsevier
Optical thermometers relying on fluorescence intensity are indispensable due to their high
sensitivity, non-contact temperature sensing capability, and exceptional repeatability. In this …