Gliomas are the most lethal primary brain tumors in adults. These highly invasive tumors
have poor 5-year survival for patients. Gliomas are principally characterized by rapid …

Glioma is the most common malignant brain tumor that develops in the glial tissue. Several
studies have identified that glioma cancer stem cells (GCSCs) play important roles in tumor …

Glioblastoma and gliomas can have a wide range of histopathologic subtypes. These
heterogeneous histologic phenotypes originate from tumor cells with the distinct functions of …

Glioblastoma (GBM) is the most common central nervous system tumor and the molecular
mechanism driving its development is still largely unknown, limiting the treatment of this …

Osteosarcoma (OS) is a rare primary malignant bone tumour arising from primitive bone-
forming mesenchymal cells, with high incidence in children and young adults, accounting for …

Abstract Phosphoinositide 3-kinase (PI3K) activity is aberrantly activated in nasopharyngeal
carcinoma. However, the underlying mechanisms remain unclear. Here, we found that …

Distant metastasis is the leading cause of treatment failure in patients with hepatocellular
carcinoma (HCC). However, the underlying mechanisms have not been fully elucidated …

Increasing reports suggest that deregulated microRNAs (miRNAs) might provide novel
therapeutic targets for cancers. However, the expression and function of miR-300 in …

The study aims to verify the hypothesis that up‐regulation of microRNA‐300 (miR‐300)
targeting CUL4B promotes apoptosis and suppresses proliferation, migration, invasion, and …

Several microRNAs (miRNAs) have been closely correlated with the development of
hepatocellular carcinoma (HCC). However, the involvement of miR-300 in the development …