Recent progresses in the pharmacological activities of caffeic acid phenethyl ester

L Lv, H Cui, Z Ma, X Liu, L Yang - Naunyn-Schmiedeberg's Archives of …, 2021 - Springer
The past decades have seen a growing interest in natural products. Caffeic acid phenethyl
ester (CAPE), a flavonoid isolated from honeybee propolis, has shown multiple …

Caffeic acid phenethyl ester as a protective agent against nephrotoxicity and/or oxidative kidney damage: a detailed systematic review

S Akyol, V Ugurcu, A Altuntas, R Hasgul… - The Scientific World …, 2014 - Wiley Online Library
Caffeic acid phenethyl ester (CAPE), an active component of propolis, has been attracting
the attention of different medical and pharmaceutical disciplines in recent years because of …

[HTML][HTML] Caffeic acid phenethyl ester protects against oxidative stress and dampens inflammation via heme oxygenase 1

A Stähli, CU Maheen, FJ Strauss, S Eick… - International journal of …, 2019 - nature.com
Periodontal disease is associated with chronic oxidative stress and inflammation. Caffeic
acid phenethyl ester (CAPE), which is a potent inducer of heme oxygenase 1 (HO1), is a …

Kidney injury and oxidative damage alleviation by Zingiber officinale: pharmacokinetics and protective approach in a combined murine model of osteoporosis

N Zammel, O Jedli, T Rebai, WS Hamadou, S Elkahoui… - 3 Biotech, 2022 - Springer
Ginger (Zingiber officinale) is considered as a nutraceutical spice, which possesses several
health promotion and benefits. This study was carried out to investigate the phyto-chemical …

Pomegranate seed extract attenuates chemotherapy-induced acute nephrotoxicity and hepatotoxicity in rats

K Çayır, A Karadeniz, N Şimşek, S Yıldırım… - Journal of medicinal …, 2011 - liebertpub.com
Cisplatin (CDDP), one of the most active cytotoxic agents against cancer, has adverse side
effects, such as nephrotoxicity and hepatotoxicity. The present study was designed to …

[HTML][HTML] Natural reno-protective agents against cyclosporine A-induced nephrotoxicity: An overview

SRM Ibrahim, HM Abdallah, AM El-Halawany… - Molecules, 2022 - mdpi.com
CA (cyclosporine A) is a powerful immunosuppressing agent that is commonly utilized for
treating various autoimmune illnesses and in transplantation surgery. However, its usage …

Caffeic acid phenethyl ester (CAPE) prevents methotrexate-induced hepatorenal oxidative injury in rats

T Çakır, E Özkan, E Dulundu… - Journal of Pharmacy …, 2011 - academic.oup.com
Objectives This study aimed to investigate the antioxidant and anti-inflammatory effects of
caffeic acid phenethyl ester (CAPE) on the methotrexate (MTX)-induced hepatorenal …

Use of antioxidants to prevent cyclosporine a toxicity

J Lee - Toxicological research, 2010 - Springer
Cyclosporine A (CsA) is a potent immunosuppressor that is widely used in transplant
surgery and the treatment of several autoimmune diseases. However, major side effects of …

Protective effect of telmisartan against cadmium-induced nephrotoxicity in mice

AA Fouad, I Jresat - Life sciences, 2011 - Elsevier
Aims To investigate the nephroprotective effect of telmisartan, the angiotensin II receptor
antagonist, against renal injury induced by cadmium in mice. Main methods Mice received …

[HTML][HTML] Pomegranate attenuates kidney injury in cyclosporine-induced nephrotoxicity in rats by suppressing oxidative stress

WI Mortada, Y Matter, SM Khater, NM Barakat… - Open …, 2023 - degruyter.com
To investigate the effect of pomegranate juice (PJ) on the cyclosporine (CsA)-induced
nephrotoxicity in rats, 80 rats were divided into four groups. The first group was regarded a …