[HTML][HTML] Pathophysiological basis and rationale for early outpatient treatment of SARS-CoV-2 (COVID-19) infection

PA McCullough, RJ Kelly, G Ruocco, E Lerma… - The American journal of …, 2021 - Elsevier
Approximately 9 months of the severe acute respiratory syndrome coronavius-2 (SARS-CoV-
2 [COVID-19]) spreading across the globe has led to widespread COVID-19 acute …

Multifaceted highly targeted sequential multidrug treatment of early ambulatory high-risk SARS-CoV-2 infection (COVID-19)

PA McCullough, PE Alexander… - Reviews in …, 2020 - scholarlycommons.henryford.com
The SARS-CoV-2 virus spreading across the world has led to surges of COVID-19 illness,
hospitalizations, and death. The complex and multifaceted pathophysiology of life …

Azithromycin and the risk of cardiovascular death

WA Ray, KT Murray, K Hall, PG Arbogast… - New England Journal …, 2012 - Mass Medical Soc
Background Although several macrolide antibiotics are proarrhythmic and associated with
an increased risk of sudden cardiac death, azithromycin is thought to have minimal …

Nonantimicrobial actions of macrolides: overview and perspectives for future development

JA Kricker, CP Page, FR Gardarsson… - Pharmacological …, 2021 - Elsevier
Macrolides are among the most widely prescribed broad spectrum antibacterials, particularly
for respiratory infections. It is now recognized that these drugs, in particular azithromycin …

A critical review on environmental presence of pharmaceutical drugs tested for the covid-19 treatment

RP Nippes, PD Macruz, GN da Silva… - Process Safety and …, 2021 - Elsevier
Abstract On March 11, 2020, the World Health Organization (WHO) declared COVID-19 a
pandemic. The outbreak caused a worldwide impact, becoming a health threat to the …

Inadequate use of antibiotics in the covid-19 era: effectiveness of antibiotic therapy

AD Bendala Estrada, J Calderón Parra… - BMC infectious …, 2021 - Springer
Abstract Background Since December 2019, the COVID-19 pandemic has changed the
concept of medicine. This work aims to analyze the use of antibiotics in patients admitted to …

The spectrum of antibiotic prescribing during COVID-19 pandemic: a systematic literature review

SH Al-Hadidi, H Alhussain, H Abdel Hadi… - Microbial Drug …, 2021 - liebertpub.com
Objectives: Over the last decades, there has been a significant increase in antimicrobial
prescribing and consumption associated with the development of patients' adverse events …

Use of azithromycin and death from cardiovascular causes

H Svanström, B Pasternak, A Hviid - New England Journal of …, 2013 - Mass Medical Soc
Background Azithromycin use is associated with an increased risk of death from
cardiovascular causes among patients at high baseline risk. Whether azithromycin confers a …

Drug safety of frequently used drugs and substances for self-medication in COVID-19

D Baracaldo-Santamaría… - … advances in drug …, 2022 - journals.sagepub.com
During the COVID-19 pandemic, the behavior of self-medication has increased. The
dissemination of misleading information regarding the efficacy of certain drugs or …

Repurposing of antibiotics for clinical management of COVID-19: a narrative review

A Yacouba, A Olowo-Okere, I Yunusa - Annals of Clinical Microbiology …, 2021 - Springer
Background Drug repurposing otherwise known as drug repositioning or drug re-profiling is
a time-tested approach in drug discovery through which new medical uses are being …