Brillouin microscopy: an emerging tool for mechanobiology

R Prevedel, A Diz-Muñoz, G Ruocco, G Antonacci - Nature methods, 2019 - nature.com
The role and importance of mechanical properties of cells and tissues in cellular function,
development and disease has widely been acknowledged, however standard techniques …

Biophysics in tumor growth and progression: from single mechano-sensitive molecules to mechanomedicine

Y Xin, K Li, M Huang, C Liang, D Siemann, L Wu, Y Tan… - Oncogene, 2023 - nature.com
Evidence from physical sciences in oncology increasingly suggests that the interplay
between the biophysical tumor microenvironment and genetic regulation has significant …

100 years of Brillouin scattering: Historical and future perspectives

M Merklein, IV Kabakova, A Zarifi… - Applied Physics …, 2022 - pubs.aip.org
The Year 2022 marks 100 years since Leon Brillouin predicted and theoretically described
the interaction of optical waves with acoustic waves in a medium. Accordingly, this resonant …

Recent progress and current opinions in Brillouin microscopy for life science applications

G Antonacci, T Beck, A Bilenca, J Czarske… - Biophysical …, 2020 - Springer
Many important biological functions and processes are reflected in cell and tissue
mechanical properties such as elasticity and viscosity. However, current techniques used for …

Diagnostic potential of blood plasma longitudinal viscosity measured using Brillouin light scattering

J Illibauer, T Clodi-Seitz, A Zoufaly, JH Aberle… - Proceedings of the …, 2024 - pnas.org
Blood plasma viscosity (PV) is an established biomarker for numerous diseases.
Measurement of the shear PV using conventional rheological techniques is, however, time …

Pulsed stimulated Brillouin microscopy enables high-sensitivity mechanical imaging of live and fragile biological specimens

F Yang, C Bevilacqua, S Hambura, A Neves… - Nature …, 2023 - nature.com
Brillouin microscopy is an emerging optical elastography technique capable of assessing
mechanical properties of biological samples in a three-dimensional, all-optical and …

High-sensitivity and high-specificity biomechanical imaging by stimulated Brillouin scattering microscopy

I Remer, R Shaashoua, N Shemesh, A Ben-Zvi… - Nature …, 2020 - nature.com
Label-free, non-contact imaging with mechanical contrast and optical sectioning is a
substantial challenge in microscopy. Spontaneous Brillouin scattering microscopy meets this …

Mapping mechanical properties of biological materials via an add-on Brillouin module to confocal microscopes

J Zhang, G Scarcelli - Nature protocols, 2021 - nature.com
Several techniques have been developed over the past few decades to assess the
mechanical properties of biological samples, which has fueled a rapid growth in the fields of …

Quantum-enhanced stimulated Brillouin scattering spectroscopy and imaging

T Li, F Li, X Liu, VV Yakovlev, GS Agarwal - Optica, 2022 - opg.optica.org
Brillouin microscopy is an emerging label-free imaging technique used to assess local
viscoelastic properties. Quantum-enhanced stimulated Brillouin scattering is demonstrated …

Methods to quantify primary plant cell wall mechanics

AJ Bidhendi, A Geitmann - Journal of Experimental Botany, 2019 - academic.oup.com
The primary plant cell wall is a dynamically regulated composite material of multiple
biopolymers that forms a scaffold enclosing the plant cells. The mechanochemical make-up …