Microglia-astrocyte crosstalk: an intimate molecular conversation
Microglia-astrocyte crosstalk has recently been at the forefront of glial research. Emerging
evidence illustrates that microglia-and astrocyte-derived signals are the functional …
evidence illustrates that microglia-and astrocyte-derived signals are the functional …
Astrocyte-derived extracellular vesicles: Neuroreparative properties and role in the pathogenesis of neurodegenerative disorders
Extracellular vesicles (EVs) released by neural cells play an essential role in brain
homeostasis and the crosstalk between neural cells and the periphery. EVs are diverse …
homeostasis and the crosstalk between neural cells and the periphery. EVs are diverse …
The emerging role of exosomes in Alzheimer's disease
T Zhang, S Ma, J Lv, X Wang, HK Afewerky, H Li… - Ageing research …, 2021 - Elsevier
Abstract Alzheimer's disease (AD), manifested by memory loss and a decline in cognitive
functions, is the most prevalent neurodegenerative disease accounting for 60–80% of …
functions, is the most prevalent neurodegenerative disease accounting for 60–80% of …
The emerging role of neural cell-derived exosomes in intercellular communication in health and neurodegenerative diseases
L Huo, X Du, X Li, S Liu, Y Xu - Frontiers in Neuroscience, 2021 - frontiersin.org
Intercellular communication in the central nervous system (CNS) is essential for brain
growth, development, and homeostasis maintenance and, when dysfunctional, is involved in …
growth, development, and homeostasis maintenance and, when dysfunctional, is involved in …
Overview and update on methods for cargo loading into extracellular vesicles
The enormous library of pharmaceutical compounds presents endless research avenues.
However, several factors limit the therapeutic potential of these drugs, such as drug …
However, several factors limit the therapeutic potential of these drugs, such as drug …
Cancer exosome-derived miR-9 and miR-181a promote the development of early-stage MDSCs via interfering with SOCS3 and PIAS3 respectively in breast cancer
M Jiang, W Zhang, R Zhang, P Liu, Y Ye, W Yu, X Guo… - Oncogene, 2020 - nature.com
We previously identified that the development of early-stage myeloid-derived suppressor
cells (eMDSCs) in breast cancer with high IL-6 (IL-6high) expression was correlated with the …
cells (eMDSCs) in breast cancer with high IL-6 (IL-6high) expression was correlated with the …
Important role of microglia in HIV-1 associated neurocognitive disorders and the molecular pathways implicated in its pathogenesis
The development of effective combined anti-retroviral therapy (cART) led to a significant
reduction in the death rate associated with human immunodeficiency virus type 1 (HIV-1) …
reduction in the death rate associated with human immunodeficiency virus type 1 (HIV-1) …
[HTML][HTML] Astrocyte-derived extracellular vesicles: A double-edged sword in central nervous system disorders
S Zhao, S Sheng, Y Wang, L Ding, X Xu, X Xia… - Neuroscience & …, 2021 - Elsevier
Recent studies suggest that astrocytes released a great quantity of EVs (AEVs) to
communicate with other brain cells. Under pathological conditions, AEVs are widely …
communicate with other brain cells. Under pathological conditions, AEVs are widely …
New challenges of HIV-1 infection: how HIV-1 attacks and resides in the central nervous system
Acquired immunodeficiency syndrome (AIDS) has become one of the most devastating
pandemics in recorded history. The main causal agent of AIDS is the human …
pandemics in recorded history. The main causal agent of AIDS is the human …
Strategies for the use of extracellular vesicles for the delivery of therapeutics
Extracellular vesicles (EVs) are nanosized, membrane-bound vesicles released from
eukaryotic and prokaryotic cells that can transport cargo containing DNA, RNA, lipids and …
eukaryotic and prokaryotic cells that can transport cargo containing DNA, RNA, lipids and …