Mechanochemistry is a promising alternative to solution-based protocols across the
chemical sciences, enabling different types of chemistries in solvent-free and …

The past decade has seen a reawakening of solid-state approaches to chemical synthesis,
driven by the search for new, cleaner synthetic methodologies. Mechanochemistry, ie …

Owing to their large ratio of surface area to mass and volume, metal–organic frameworks
and porous carbons have revolutionized many applications that rely on chemical and …

As small molecule drugs become harder to develop and less cost effective for patient use,
efficient strategies for their property improvement become increasingly important to global …

This overview highlights the emergent area of mechanochemical reactions for making active
pharmaceutical ingredients (APIs), and covers the latest advances in the recently …

Mechanochemistry of inorganic solids is a well-established field. In the last decade
mechanical treatment has become increasingly popular as a method for achieving selective …

In recent years cocrystal formation has emerged as a viable strategy towards improving the
solubility and bioavailability of poorly soluble drugs. In this review the success of numerous …

Chemical and structural transformations have long been carried out by milling. Such
mechanochemical steps are now ubiquitous in a number of industries (such as the …

Recently, the application of mechanochemical strategies in organic synthesis has attracted
the attention of both the academic and industrial chemical communities. The high efficiency …

We provide a brief overview of recent advances in the use of mechanochemical techniques
for the synthesis of organic molecules and materials, highlighting selected examples of …