Insulin resistance is a main determinant in the development of type 2 diabetes mellitus and a
major cause of morbidity and mortality. The circadian timing system consists of a central …

Peroxisome proliferator–activated receptors (PPARs) regulate energy metabolism and
hence are therapeutic targets in metabolic diseases such as type 2 diabetes and non …

It has been more than 36 years since peroxisome proliferator-activated receptors (PPARs)
were first recognized as enhancers of peroxisome proliferation. Consequently, many studies …

Each day, all organisms are subjected to changes in light intensity because of the Earth's
rotation around its own axis. To anticipate this geo-physical variability, and to appropriately …

Nutrient metabolism is under circadian regulation. Disruption of circadian rhythms by
lifestyle and behavioral choices such as work schedules, eating patterns, and social jetlag …

The control of proteins by a transcription factor with periodically varying concentration
exhibits intriguing dynamical behaviour. Even though it is accepted that transcription factors …

Lysine acetylation is involved in various biological processes and is considered a key
reversible post-translational modification in the regulation of gene expression, enzyme …

Men and women exhibit notable differences not only in the reproductive system and
reproductive behaviors, but in many other organ and physiological systems as well. Notable …

Entrainment denotes a process of coordinating the internal circadian clock to external
rhythmic time-cues (Zeitgeber), mainly light. It is facilitated by stronger Zeitgeber signals and …

Circadian rhythms are endogenous~ 24‐hr oscillations usually entrained to daily
environmental cycles of light/dark. Many biological processes and physiological functions …