Glycomic and glycoproteomic analyses involve the characterization of oligosaccharides
(glycans) conjugated to proteins. Glycans are produced through a complicated nontemplate …

Notes 408 Biographies 408 Acknowledgments 409 References 409 The enormous
structural diversity of glycoconjugates mirrors their myriad biological functions in prokaryotic …

The inclusion of preliminary chemical labeling (derivatization) in the analysis process by
such powerful and widespread methods as electrospray ionization (ESI) and matrix-assisted …

The applications of organic matrices for matrix assisted laser desorption/ionization mass
spectrometry (MALDI-MS) are reviewed. Recent advances of MALDI-MS using organic …

This review is the eighth update of the original article published in 1999 on the application of
Matrix‐assisted laser desorption/ionization mass spectrometry (MALDI) mass spectrometry …

Sialic acids usually locate at the terminal of many glycan structures in either α (2, 3) or α (2,
6) linkage, playing different roles in various biological and pathological processes. Several …

Glycosylation can be a critical quality attribute for protein therapeutics due to its extensive
impact on product safety and efficacy. Glycan characterization is important in the process of …

Quantitative N-glycomics provides an effective tool for detecting glycosylation changes in
cancer and other diseases. However, the lability of sialic acid and its lower ionization …

To characterize the structures of N-glycans derived from human serum, we report a strategy
that combines microchip electrophoresis, standard addition, enzymatic digestion, and matrix …

Background Many treatment options especially for cancer show a low efficacy for the
majority of patients demanding improved biomarker panels for patient stratification. Changes …