A principal purpose of type 2 immunity was thought to be defense against large parasites,
but it also functions in the restoration of homeostasis, such as toxin clearance following …

Summary T helper 17 (Th17) cells regulate mucosal barrier defenses but also promote
multiple autoinflammatory diseases. Although many molecular determinants of Th17 cell …

Maresin-1 is one of the representative specialized pro-resolving mediators that has shown
beneficial effects in inflammatory disease models. Recently, two distinct types of receptor …

Mice with a loss-of-function mutation in the LAT adaptor (LatY136F) develop an autoimmune
and type 2 inflammatory disorder called defective LAT signalosome pathology (DLSP). We …

Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), is a global
health concern, yearly resulting in 10 million new cases of active TB. Immunologic …

The advent of single-cell multi-omics sequencing technology makes it possible for
researchers to leverage multiple modalities for individual cells and explore cell …

Myocarditis has emerged as an immune-related adverse event of immune checkpoint
inhibitor (ICI) cancer therapy associated with significant mortality. To ensure patients …

During infections, the timings of effector differentiation of pulmonary immune responses are
of paramount importance, as pathogen persistence and unsuppressed inflammation can …

Cytokine secretion, such as interleukin‐4 (IL‐4), IL‐5, IL‐9, IL‐13, and amphiregulin (Areg),
by type 2 innate lymphoid cells (ILC2s) is indispensable for homeostasis …

Photodynamic therapy (PDT) has shown promise in reducing metastatic colorectal cancer
(CRC); however, the underlying mechanisms remain unclear. Modulating tumor-infiltrating …