Physical cues like morphology, light, electric signal, mechanic signal, magnetic signal, and
heat can be used as alternative regulators for expensive but short‐acting growth factors in …

Large bone defects are a major global health concern. Bone tissue engineering (BTE) is the
most promising alternative to avoid the drawbacks of autograft and allograft bone …

Osteoporosis, characterized by an imbalance in bone homeostasis, is a global health
concern. Bone defects are difficult to heal in patients with osteoporosis. Classical drug …

Mineralized collagen (MC) is the basic unit of bone structure and function and is the main
component of the extracellular matrix (ECM) in bone tissue. In the biomimetic method, MC …

The development of 3D printing technologies has allowed us to fabricate complex novel
scaffolds for bone regeneration. In this study, we reported the incorporation of different …

The origin of life and native tissue development are dependent on the heterogeneity of
pluripotent stem cells. Bone marrow mesenchymal stem cells (BMMSCs) are located in a …

Cells are known to perceive their microenvironment through extracellular and intracellular
mechanical signals. Upon sensing mechanical stimuli, cells can initiate various downstream …

The temporospatial equilibrium of phosphate contributes to physiological bone development
and fracture healing, yet optimal control of phosphate content has not been explored in …

Osteoporosis is a prevalent chronic metabolic bone disease that poses a significant risk of
fractures or mortality in elderly individuals. Its pathophysiological basis is often attributed to …

Custom synthesis of extracellular matrix (ECM)-inspired materials for condition-specific
reconstruction has emerged as a potentially translatable regenerative strategy. In skull …