Toxicity of amphetamines: an update

M Carvalho, H Carmo, VM Costa, JP Capela… - Archives of …, 2012 - Springer
Amphetamines represent a class of psychotropic compounds, widely abused for their
stimulant, euphoric, anorectic, and, in some cases, emphathogenic, entactogenic, and …

Amphetamine-related drugs neurotoxicity in humans and in experimental animals: Main mechanisms

R Moratalla, A Khairnar, N Simola, N Granado… - Progress in …, 2017 - Elsevier
Amphetamine-related drugs, such as 3, 4-methylenedioxymethamphetamine (MDMA) and
methamphetamine (METH), are popular recreational psychostimulants. Several preclinical …

A systematic prediction of multiple drug-target interactions from chemical, genomic, and pharmacological data

H Yu, J Chen, X Xu, Y Li, H Zhao, Y Fang, X Li, W Zhou… - PloS one, 2012 - journals.plos.org
In silico prediction of drug-target interactions from heterogeneous biological data can
advance our system-level search for drug molecules and therapeutic targets, which efforts …

Imaging by flat lens using negative refraction

PV Parimi, WT Lu, P Vodo, S Sridhar - Nature, 2003 - nature.com
The positive refractive index of conventional optical lenses means that they need curved
surfaces to form an image, whereas a negative index of refraction allows a flat slab of a …

Mechanisms of action and persistent neuroplasticity by drugs of abuse

ER Korpi, B den Hollander, U Farooq… - Pharmacological …, 2015 - ASPET
Adaptation of the nervous system to different chemical and physiologic conditions is
important for the homeostasis of brain processes and for learning and remembering …

Molecular and cellular mechanisms of ecstasy-induced neurotoxicity: an overview

JP Capela, H Carmo, F Remião, ML Bastos… - Molecular …, 2009 - Springer
Abstract “Ecstasy”[(±)-3, 4-methylenedioxymethamphetamine, MDMA, XTC, X, E] is a
psychoactive recreational hallucinogenic substance and a major worldwide drug of abuse …

Thyroid–adrenergic interactions: physiological and clinical implications

JE Silva, SDC Bianco - Thyroid, 2008 - liebertpub.com
The sympathoadrenal system, including the sympathetic nervous system and the adrenal
medulla, interacts with thyroid hormone (TH) at various levels. Both systems are evolutionary …

Neurotoxicity of substituted amphetamines: molecular and cellular mechanisms

JL Cadet, IN Krasnova, S Jayanthi, J Lyles - Neurotoxicity research, 2007 - Springer
The amphetamines, including amphetamine (AMPH), methamphetamine (METH) and 3, 4-
methylenedioxymethamphetamine (MDMA), are among abused drugs in the US and …

Uncoupling the agony from ecstasy

EM Mills, ML Banks, JE Sprague, T Finkel - Nature, 2003 - nature.com
The recreational use of amphetamine-type stimulants can produce a marked and sometimes
lethal increase in body temperature. Here we show that mice deficient in a mitochondrial …

MDMA and temperature: a review of the thermal effects of 'Ecstasy'in humans

AC Parrott - Drug and alcohol dependence, 2012 - Elsevier
AIMS: To review the thermal effects of MDMA in humans, and discuss the practical
implications. METHODS: The literature on Ecstasy/MDMA, body temperature, and subjective …