A molecular basis of tumor metastasis and current approaches to decode targeted migration-promoting events in pediatric neuroblastoma

D Corallo, M Dalla Vecchia, D Lazic… - Biochemical …, 2023 - Elsevier
Cell motility is a crucial biological process that plays a critical role in the development of
multicellular organisms and is essential for tissue formation and regeneration. However …

Beyond the centrosome: The mystery of microtubule organising centres across mammalian preimplantation embryos

SP Martínez, J Greaney, J Zenker - Current Opinion in Cell Biology, 2022 - Elsevier
Mammalian preimplantation embryogenesis depends on the spatio-temporal dynamics of
the microtubule cytoskeleton to enable exceptionally fast changes in cell number, function …

Current and future applications of light-sheet imaging for identifying molecular and developmental processes in autism spectrum disorders

A Soumier, G Lio, C Demily - Molecular Psychiatry, 2024 - nature.com
Autism spectrum disorder (ASD) is identified by a set of neurodevelopmental divergences
that typically affect the social communication domain. ASD is also characterized by …

Dynamics of Drosophila endoderm specification

SE Keenan, M Avdeeva, L Yang… - Proceedings of the …, 2022 - National Acad Sciences
During early Drosophila embryogenesis, a network of gene regulatory interactions
orchestrates terminal patterning, playing a critical role in the subsequent formation of the gut …

Viewing early life without labels: optical approaches for imaging the early embryo

DJX Chow, TCY Tan, A Upadhya, M Lim… - Biology of …, 2024 - academic.oup.com
Embryo quality is an important determinant of successful implantation and a resultant live
birth. Current clinical approaches for evaluating embryo quality rely on subjective …

Embryo Development in a Stochastic Universe

EC Elson - Bioelectricity, 2024 - liebertpub.com
Despite the elucidation of the many processes by which a single eukaryotic cell develops
into a complex mature organism, it is still puzzling to some biologists how it is that an …

A practical guide to light-sheet microscopy for nanoscale imaging: Looking beyond the cell

SN Kramer, J Antarasen, CR Reinholt… - arXiv preprint arXiv …, 2024 - arxiv.org
We present a comprehensive guide to light-sheet microscopy (LSM) to assist scientists in
navigating the practical implementation of this microscopy technique. Emphasizing the …

Multiple asters organize the yolk microtubule network during dclk2-GFP zebrafish epiboly

M Marsal, M Bernardello, EJ Gualda, P Loza-Alvarez - Scientific reports, 2022 - nature.com
It is known that the organization of microtubule (MT) networks in cells is orchestrated by
subcellular structures named MT organizing centers (MTOCs). In this work, we use Light …

Design and Build of a Customizable Light Sheet for Visualization of Cytoskeleton Networks

N Felcher, D Achiriloaie, B Lee, R McGorty… - arXiv preprint arXiv …, 2023 - arxiv.org
Reconstituted cytoskeleton composites have emerged as a valuable model system for
studying non equilibrium soft matter. Faithful capture of the dynamics of these three …

Author Spotlight: Advancing Knowledge in Far-From-Equilibrium Materials Through Light-Sheet Microscopy

N Felcher, D Achiriloaie, B Lee, R McGorty… - JoVE (Journal of …, 2024 - jove.com
Reconstituted cytoskeleton composites have emerged as a valuable model system for
studying non-equilibrium soft matter. The faithful capture of the dynamics of these 3D, dense …