With the identification of novel targets, the number of interventional clinical trials in
ophthalmology has increased. Visual acuity has for a long time been considered the gold …

Background Stargardt disease (STGD1) is an autosomal recessive retinal dystrophy due to
mutations in ABCA4, characterized by subretinal deposition of lipofuscin-like substances …

Stargardt macular dystrophy (Stargardt disease; STGD1; OMIM 248200) is the most
prevalent inherited macular dystrophy. STGD1 is an autosomal recessive disorder caused …

Functional assessments are a fundamental part of the clinical evaluation of patients with
inherited retinal diseases (IRDs). Their importance and impact have become increasingly …

Purpose: The purpose of this study was to evaluate rod-mediated function with two-color
dark-adapted perimetry (2cDAP) in patients with RPE65-related retinopathy treated with …

Retinal microperimetry (MP) is a procedure that assesses the retinal sensitivity while the
fundus is directly observed, and an eye tracker system is active to compensate for …

The aim of this review article is to describe the specific features of Stargardt disease and
ABCA4 retinopathies (ABCA4R) using multimodal imaging and functional testing and to …

Purpose To establish disease progression rates in total lesion size (TLS), decreased
autofluorescence (DAF) area, total macular volume (TMV), and mean macular sensitivity …

Purpose: To investigate and compare novel volumetric microperimetry (MP)–derived metrics
in intermediate age-related macular degeneration (iAMD), as current MP metrics show high …

Purpose To evaluate progression rate estimation in long-term Stargardt disease
microperimetry data by accounting for floor effect. Design Cohort study. Subjects Thirty …