Toward multi-targeted platinum and ruthenium drugs—a new paradigm in cancer drug treatment regimens?
RG Kenny, CJ Marmion - Chemical reviews, 2019 - ACS Publications
While medicinal inorganic chemistry has been practised for over 5000 years, it was not until
the late 1800s when Alfred Werner published his ground-breaking research on coordination …
the late 1800s when Alfred Werner published his ground-breaking research on coordination …
Peptides and peptide hormones for molecular imaging and disease diagnosis
Molecular imaging techniques are now indispensable tools in modern diagnostics, because
they are highly specific and can provide biological information at the molecular level in living …
they are highly specific and can provide biological information at the molecular level in living …
Photocontrolled DNA binding of a receptor-targeted organometallic ruthenium (II) complex
F Barragán, P López-Senín, L Salassa… - Journal of the …, 2011 - ACS Publications
A photoactivated ruthenium (II) arene complex has been conjugated to two receptor-binding
peptides, a dicarba analogue of octreotide and the Arg-Gly-Asp (RGD) tripeptide. These …
peptides, a dicarba analogue of octreotide and the Arg-Gly-Asp (RGD) tripeptide. These …
Quorumpeps database: chemical space, microbial origin and functionality of quorum sensing peptides
E Wynendaele, A Bronselaer, J Nielandt… - Nucleic acids …, 2013 - academic.oup.com
Quorum-sensing (QS) peptides are biologically attractive molecules, with a wide diversity of
structures and prone to modifications altering or presenting new functionalities. Therefore …
structures and prone to modifications altering or presenting new functionalities. Therefore …
Integrin-targeted delivery into cancer cells of a Pt (IV) pro-drug through conjugation to RGD-containing peptides
A Massaguer, A González-Cantó, E Escribano… - Dalton …, 2015 - pubs.rsc.org
Conjugates of a Pt (IV) derivative of picoplatin with monomeric (Pt–c (RGDfK), 5) and
tetrameric (Pt–RAFT-{c (RGDfK)} 4, 6) RGD-containing peptides were synthesized with the …
tetrameric (Pt–RAFT-{c (RGDfK)} 4, 6) RGD-containing peptides were synthesized with the …
Multiple antigenic peptide (MAP): a synthetic peptide dendrimer for diagnostic, antiviral and vaccine strategies for emerging and re-emerging viral diseases
The peptide dendrimer provides novel strategies for various biological applications.
Assembling of peptide in macromolecular structure is expected to give rational models as …
Assembling of peptide in macromolecular structure is expected to give rational models as …
The role of cholecystokinin receptors in the short-term control of food intake
AI Sayegh - Progress in molecular biology and translational …, 2013 - Elsevier
Cholecystokinin (CCK) is a hormone secreted by the I-cells of the upper small intestine in
response to fat, protein, and some nonnutrients, for example, camostat, and a peptide …
response to fat, protein, and some nonnutrients, for example, camostat, and a peptide …
Next Generation of SiFAlin-Based TATE Derivatives for PET Imaging of SSTR-Positive Tumors: Influence of Molecular Design on In Vitro SSTR Binding and In Vivo …
S Litau, S Niedermoser, N Vogler… - Bioconjugate …, 2015 - ACS Publications
The Silicon-Fluoride-Acceptor (SiFA)-18F-labeling strategy has been shown before to
enable the straightforward and efficient 18F-labeling of complex biologically active …
enable the straightforward and efficient 18F-labeling of complex biologically active …
Evaluation of the anti-angiogenic properties of the new selective αVβ3 integrin antagonist RGDechiHCit
G Santulli, MF Basilicata, M De Simone… - Journal of translational …, 2011 - Springer
Background Integrins are heterodimeric receptors that play a critical role in cell-cell and cell-
matrix adhesion processes. Among them, α V β 3 integrin, that recognizes the aminoacidic …
matrix adhesion processes. Among them, α V β 3 integrin, that recognizes the aminoacidic …
Somatostatin subtype-2 receptor-targeted metal-based anticancer complexes
F Barragán, D Carrion-Salip, I Gómez-Pinto… - Bioconjugate …, 2012 - ACS Publications
Conjugates of a dicarba analogue of octreotide, a potent somatostatin agonist whose
receptors are overexpressed on tumor cells, with [PtCl2 (dap)](dap= 1-(carboxylic acid)-1, 2 …
receptors are overexpressed on tumor cells, with [PtCl2 (dap)](dap= 1-(carboxylic acid)-1, 2 …