Toward multi-targeted platinum and ruthenium drugs—a new paradigm in cancer drug treatment regimens?

RG Kenny, CJ Marmion - Chemical reviews, 2019 - ACS Publications
While medicinal inorganic chemistry has been practised for over 5000 years, it was not until
the late 1800s when Alfred Werner published his ground-breaking research on coordination …

Peptides and peptide hormones for molecular imaging and disease diagnosis

S Lee, J Xie, X Chen - Chemical reviews, 2010 - ACS Publications
Molecular imaging techniques are now indispensable tools in modern diagnostics, because
they are highly specific and can provide biological information at the molecular level in living …

Photocontrolled DNA binding of a receptor-targeted organometallic ruthenium (II) complex

F Barragán, P López-Senín, L Salassa… - Journal of the …, 2011 - ACS Publications
A photoactivated ruthenium (II) arene complex has been conjugated to two receptor-binding
peptides, a dicarba analogue of octreotide and the Arg-Gly-Asp (RGD) tripeptide. These …

Quorumpeps database: chemical space, microbial origin and functionality of quorum sensing peptides

E Wynendaele, A Bronselaer, J Nielandt… - Nucleic acids …, 2013 - academic.oup.com
Quorum-sensing (QS) peptides are biologically attractive molecules, with a wide diversity of
structures and prone to modifications altering or presenting new functionalities. Therefore …

Integrin-targeted delivery into cancer cells of a Pt (IV) pro-drug through conjugation to RGD-containing peptides

A Massaguer, A González-Cantó, E Escribano… - Dalton …, 2015 - pubs.rsc.org
Conjugates of a Pt (IV) derivative of picoplatin with monomeric (Pt–c (RGDfK), 5) and
tetrameric (Pt–RAFT-{c (RGDfK)} 4, 6) RGD-containing peptides were synthesized with the …

Multiple antigenic peptide (MAP): a synthetic peptide dendrimer for diagnostic, antiviral and vaccine strategies for emerging and re-emerging viral diseases

VG Joshi, VD Dighe, D Thakuria, YS Malik… - Indian Journal of …, 2013 - Springer
The peptide dendrimer provides novel strategies for various biological applications.
Assembling of peptide in macromolecular structure is expected to give rational models as …

The role of cholecystokinin receptors in the short-term control of food intake

AI Sayegh - Progress in molecular biology and translational …, 2013 - Elsevier
Cholecystokinin (CCK) is a hormone secreted by the I-cells of the upper small intestine in
response to fat, protein, and some nonnutrients, for example, camostat, and a peptide …

Next Generation of SiFAlin-Based TATE Derivatives for PET Imaging of SSTR-Positive Tumors: Influence of Molecular Design on In Vitro SSTR Binding and In Vivo …

S Litau, S Niedermoser, N Vogler… - Bioconjugate …, 2015 - ACS Publications
The Silicon-Fluoride-Acceptor (SiFA)-18F-labeling strategy has been shown before to
enable the straightforward and efficient 18F-labeling of complex biologically active …

Evaluation of the anti-angiogenic properties of the new selective αVβ3 integrin antagonist RGDechiHCit

G Santulli, MF Basilicata, M De Simone… - Journal of translational …, 2011 - Springer
Background Integrins are heterodimeric receptors that play a critical role in cell-cell and cell-
matrix adhesion processes. Among them, α V β 3 integrin, that recognizes the aminoacidic …

Somatostatin subtype-2 receptor-targeted metal-based anticancer complexes

F Barragán, D Carrion-Salip, I Gómez-Pinto… - Bioconjugate …, 2012 - ACS Publications
Conjugates of a dicarba analogue of octreotide, a potent somatostatin agonist whose
receptors are overexpressed on tumor cells, with [PtCl2 (dap)](dap= 1-(carboxylic acid)-1, 2 …