What is polypharmacy? A systematic review of definitions

N Masnoon, S Shakib, L Kalisch-Ellett, GE Caughey - BMC geriatrics, 2017 - Springer
Background Multimorbidity and the associated use of multiple medicines (polypharmacy), is
common in the older population. Despite this, there is no consensus definition for …

Functional versus chronological age: geriatric assessments to guide decision making in older patients with cancer

E Soto-Perez-de-Celis, D Li, Y Yuan, YM Lau… - The Lancet …, 2018 - thelancet.com
As the worldwide population ages, oncologists are often required to make difficult and
complex decisions regarding the treatment of older people (aged 65 years and older) with …

Practical assessment and management of vulnerabilities in older patients receiving chemotherapy: ASCO guideline for geriatric oncology

SG Mohile, W Dale, MR Somerfield… - Journal of clinical …, 2018 - ascopubs.org
Purpose To provide guidance regarding the practical assessment and management of
vulnerabilities in older patients undergoing chemotherapy. Methods An Expert Panel was …

Clinical consequences of polypharmacy in elderly

RL Maher, J Hanlon, ER Hajjar - Expert opinion on drug safety, 2014 - Taylor & Francis
Introduction: Polypharmacy, defined as the use of multiple drugs or more than are medically
necessary, is a growing concern for older adults. MEDLINE and EMBASE databases were …

Evaluation of a pharmacist-led medication assessment used to identify prevalence of and associations with polypharmacy and potentially inappropriate medication …

G Nightingale, E Hajjar, K Swartz… - Journal of Clinical …, 2015 - ascopubs.org
Purpose The use of multiple and/or inappropriate medications in seniors is a significant
public health problem, and cancer treatment escalates its prevalence and complexity …

Associations of polypharmacy and inappropriate medications with adverse outcomes in older adults with cancer: a systematic review and meta‐analysis

MR Mohamed, E Ramsdale, KP Loh, A Arastu… - The …, 2020 - academic.oup.com
Background Polypharmacy (PP) and potentially inappropriate medications (PIM) are highly
prevalent in older adults with cancer. This study systematically reviews the associations of …

Polypharmacy and potentially inappropriate medication use in geriatric oncology

M Sharma, KP Loh, G Nightingale, SG Mohile… - Journal of geriatric …, 2016 - Elsevier
Polypharmacy is a highly prevalent problem in older persons, and is challenging to assess
and improve due to variations in definitions of the problem and the heterogeneous methods …

A practical guide to geriatric syndromes in older adults with cancer: a focus on falls, cognition, polypharmacy, and depression

A Magnuson, S Sattar, G Nightingale… - American Society of …, 2019 - ascopubs.org
Geriatric syndromes are multifactorial conditions that are prevalent in older adults. Geriatric
syndromes are believed to develop when an individual experiences accumulated …

A systematic review of randomised-controlled trials on deprescribing outcomes in older adults with polypharmacy

H Omuya, C Nickel, P Wilson… - International Journal of …, 2023 - academic.oup.com
Background Mixed findings about deprescribing impact have emerged from varied study
designs, interventions, outcome measures and targeting sub-categories of medications or …

[HTML][HTML] Management of pancreatic cancer in the elderly

O Higuera, I Ghanem, R Nasimi, I Prieto… - World journal of …, 2016 - ncbi.nlm.nih.gov
Currently, pancreatic adenocarcinoma mainly occurs after 60 years of age, and its prognosis
remains poor despite modest improvements in recent decades. The aging of the population …