Prenatal Zika virus infection has sex-specific effects on infant physical development and mother-infant social interactions

G Moadab, F Pittet, JL Bennett, CL Taylor… - Science Translational …, 2023 - science.org
There is enormous variation in the extent to which fetal Zika virus (fZIKV) infection affects the
developing brain. Despite the neural consequences of fZIKV infection observed in people …

Continuing development of vaccines and monoclonal antibodies against Zika virus

SE Woodson, KM Morabito - npj Vaccines, 2024 - nature.com
The 2016 Zika virus (ZIKV) epidemic catalyzed a global effort to develop diagnostic tests,
vaccines, and therapeutic treatments. However, the rapid waning epidemiology of ZIKV …

Treatment with sofosbuvir attenuates the adverse neurodevelopmental consequences of Zika virus infection in infant rhesus macaques

A Medina, R Rusnak, R Richardson… - Journal of …, 2023 - Elsevier
Zika virus (ZIKV) infection during infancy in a rhesus macaque (RM) model negatively
impacts brain development resulting in long-term behavioral alterations. The current study …

Ferumoxytol dynamic contrast enhanced magnetic resonance imaging identifies altered placental cotyledon perfusion in rhesus macaques

DP Seiter, SM Nguyen, TK Morgan, L Mao… - Biology of …, 2022 - academic.oup.com
Identification of placental dysfunction in early pregnancy with noninvasive imaging could be
a valuable tool for assessing maternal and fetal risk. Dynamic contrast enhanced (DCE) …

Fetal Zika virus inoculation in macaques revealed control of the fetal viral load during pregnancy

C Egloff, CM Fovet, J Denis, Q Pascal, L Bossevot… - Virology Journal, 2024 - Springer
Abstract Background Early pregnancy Zika virus (ZIKV) infection is associated with major
brain damage in fetuses, leading to microcephaly in 0.6–5.0% of cases, but the underlying …

Prenatal Zika Virus Exposure Alters the Interaction Between Affective Processing and Decision‐Making in Juvenile Rhesus Macaques (Macaca mulatta)

PR Cogo, G Moadab, E Bliss‐Moreau… - Developmental …, 2024 - Wiley Online Library
Many challenges during pregnancy can disrupt fetal development and have varying
consequences on the subsequent psychological development of infants. Notably, exposure …

Prenatal Zika virus exposure is associated with lateral geniculate nucleus abnormalities in juvenile rhesus macaques

EE Ball, JL Bennett, RI Keesler, KKA Van Rompay… - …, 2023 - journals.lww.com
Zika virus' neural tropism causes significant neural pathology, particularly in developing
fetuses. One of the consistent findings from humans and animal models is that prenatal …