proBDNF/p75NTR promotes rheumatoid arthritis and inflammatory response by activating proinflammatory cytokines

CR Yang, HJ Ding, M Yu, FH Zhou, CY Han… - The FASEB …, 2022 - Wiley Online Library
P75 pan‐neurotrophin receptor (p75NTR) is an important receptor for the role of
neurotrophins in survival and death of neurons during development and after nerve injury …

[HTML][HTML] p75ECD-Fc reverses neonatal hypoxic-ischemic encephalopathy-induced neurological deficits and inhibits apoptosis associated with Nestin

QX Xiao, LL Xue, YX Tan, LR Huangfu, L Chen… - Biomedicine & …, 2024 - Elsevier
A recent study has introduced a recombinant fusion protein, consisting of the extracellular
domain (ECD) of p75 and the Fc fragment of human immunoglobulin IgG1 (p75ECD-Fc), as …